Magnitude of Residue Studies in Pesticide Registration Field Trials and Crop Grouping
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1 Magnitude of Residue Studies in Pesticide Registration Field Trials and Crop Grouping Johannes Corley, Daniel Kunkel, Jerry Baron IR-4 HQ, Rutgers the State University of New Jersey 500 College Rd. East # 201 W. Princeton, NJ jcorley@aesop.rutgers.edu
2 Overview of Presentation Focus on Magnitude of Residue Studies Specialty crops and IR-4 Residue expression and analytes of concern Study set-up Location of field trials Transportation of samples, to cut or not to cut, that is the question Analytical phase Crop Grouping Collaboration throughout NAFTA Harmonization
3 Major Crops > 200,000 Acres Corn Cotton Rice horticultureintheord.files.wordpress.com Soybean Wheat img.breakingmuscle.com Etc.
4 Specialty Crops and IR-4 Cherry Sunflower Hops Ginseng Watercress Cranberry
5 Residue Expression & Analytes of Concern U.S. Residue Expression: Fenpyrazamine: Fenpyrazamine S-allyl 5-amino-2-isopropyl-4-(2- methylphenyl)-3-oxo-2,3-dihydropyrazole-1-carbothioate Zoxamide: Zoxamide and its metabolites 3,5-dichloro-1,4- benzenedicarboxylic acid and 3,5-dichloro-4-hydroxymethylbenzoic acid Propiconazole: Propiconazole 1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3- dioxolan-2-yl] methyl]-1h-1,2,4-triazole and its metabolites determined as 2,4-dichlorobenzoic acid and expressed as parent compound
6 Study Setup and Planning Planning a Magnitude of Residue Study involves coordinating both field and analysis phases. All under US EPA Good Laboratory Practice Standards. Determining a use pattern (based on efficacy studies) Matching use patterns from different parts of the country Choosing a use pattern that would provide residue data in a worst case scenario Ensuring that the use pattern will not result in unfavorable residues or harm the crop or the environment
7 Crop Total # of trials Location of Field Trials EPA Guidelines Number of trials in each NAFTA region Asparagus Avocado Carrot Tomato
8 Conduct of a field trial - Application
9 Conduct of a field trial Sampling
10 Analytical Phase
11 Crop Grouping CITRUS FRUIT GROUP 10-10A. Orange subgroup 10-10B. Lemon/Lime subgroup 10-10C. Grapefruit subgroup Orange or tangerine/mandarin, lemon or lime, and grapefruit Orange or tangerine/mandarin Lemon or lime Grapefruit Australian desert lime; Australian finger-lime; Australian round lime; Brown River finger lime; calamondin; citron; citrus hybrids; grapefruit; Japanese summer grapefruit; kumquat; lemon; lime; Mediterranean mandarin; mount white lime; New Guinea wild lime; orange, sour; orange, sweet; pummelo; Russell River lime; satsuma mandarin; sweet lime; tachibana orange; Tahiti lime; tangelo; tangerine (mandarin); tangor; trifoliate orange; uniq fruit; cultivars, varieties, and/or hybrids of these Calamondin; citron; citrus hybrids; Mediterranean mandarin; orange, sour; orange, sweet; satsuma mandarin; tachibana orange; tangerine (mandarin); tangelo, tangor; trifoliate orange; cultivars, varieties, and/or hybrids of these Australian desert lime; Australian finger-lime; Australian round lime; brown river finger lime; kumquat; lemon; lime; mount white lime; New Guinea wild lime; Russell River lime; sweet lime; Tahiti lime; cultivars, varieties, and/or hybrids of these Grapefruit; Japanese summer grapefruit; pummelo; tangelo; uniq fruit; cultivars, varieties, and/or hybrids of these Source: IR-4 Website:
12 Crop Grouping FRUITING VEGETABLE GROUP Tomato, standard size, and one cultivar of small tomato; bell pepper and one cultivar of small non-bell pepper African eggplant; bush tomato; bell pepper; cocona; currant tomato; eggplant; garden huckleberry; goji berry; groundcherry; martynia; naranjilla; okra; pea eggplant; pepino; non-bell pepper; roselle; scarlet eggplant; sunberry; tomatillo; tomato; tree tomato; cultivars, varieties, and/or hybrids of these 8-10A. Tomato subgroup Tomato (standard size and one cultivar of small tomato) Bush tomato; cocona; currant tomato; garden huckleberry; goji berry; groundcherry; naranjilla; sunberry; tomatillo; tomato; tree tomato; cultivars, varieties, and/or hybrids of these 8-10B. Pepper/Eggplant subgroup Bell pepper and one cultivar of small non-bell pepper African eggplant; bell pepper; eggplant; martynia; non-bell pepper; okra; pea eggplant; pepino; roselle; scarlet eggplant; cultivars, varieties, and/or hybrids of these 8-10C. One cultivar of small non-bell pepper or Nonbell pepper/eggplant one cultivar of small eggplant subgroup Source: IR-4 Website: and/or hybrids of these Source: IR-4 Website: African eggplant; eggplant; martynia; non-bell pepper; okra; pea eggplant; pepino; roselle; scarlet eggplant ; cultivars, varieties,
13 NAFTA Harmonization, a Success Story
14 Harmonization of Regulatory Requirements Some important factors to be considered in simplifying global food trade: Harmonization of residue testing guidelines Harmonization of residue expressions Harmonization of trial requirements Using a standardized method to calculate MRL s Greater acceptance of Codex MRL s at least for import/export purposes
15 Acknowledgements Funding for IR-4 is received from: USDA-NIFA USDA-FAS Additional support for IR-4 research is received from: USDA-ARS U.S. State Land Grant Universities Unless otherwise stated, all pictures are from IR-4 trials and crop tours
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