NERUDIA CONSULTING LIMITED WELLINGTON HOUSE, PHYSICS ROAD, SPEKE BOULEVARD, SPEKE, LIVERPOOL L24 9HP

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1 V-TOX INGREDIENTS V-Tox is a database comprising toxicological data which has been generated from scientific literature. FOR MORE INFORMATION compliance@nerudia.com OR CALL US ON +44 (0) The database consists of 350+ ingredients found in e-liquid and compounds found in e-cigarette emissions, for which we have completed a toxicological literature search. INGREDIENT NAME CAS NUMBER acetal acetanisole acetoin acetic acid acetone acetophenone acetyl furan acetyl-5-methylsulfuran acetyl propionyl acetylpyrazine acetylpyridine acetylpyridine acetylthiazole allyl cyclohexylpropionate allyl hexanoate alpha-angelicalactone alpha-damascone alpha-ionone alpha-isomethylionone alpha-methylbenzyl acetate alpha-phellandrene alpha-terpineol / a-methylbenzylalcohol amyl alcohol amyl-alpha-pyrone amyl butyrate Amyris oil (Amyris Balsamifera L) anethole (trans-) Anise alcohol PAGE 1

2 anisyl acetate Apple juice concentrate Balsam Peru (Myroxylon pereirae Klotz) benzyl acetate benzyl alcohol benzaldehyde benzyl benzoate benzyl butyrate benzyl cinnamate benzylidene acetone benzyl isovalerate benzyl propionate beta-caryophyllene beta-damascenone beta-damascone beta-ionone beta pinene blackcurrant buds abs (Ribes nigrum) borneol bornyl acetate Buchu leaf oil (barosma spp.) butanedioic acid, monomenthyl ester butyl acetate butyl alcohol butyl isovalerate butyl lactate butyric acid (N-) camphene caramel syrup carrot seed oil (Daucus carota L.) carvacrole carvones caryophyllene oxide Cassia bark oil (Cinnam. Cassia Blume) cedarwood oil (Juniperus virginiana l.) chamomile oil hungaria (matricaria cham) cinammic alcohol cinnamic aldehyde Cinnamon bark oil (Cinnamomum spp.) cinnamyl acetate cinnamyl isovalerate cis-3-hexenol cis-3-hexen-1-yl- acetate cis-3-hexenyl butyrate cis-3-hexenylformate PAGE 2

3 cis-3-hexenyl hexanoate cis-3-hexenyl isovalerate cis-3-hexenylpropionate cis-jasmone cis-6-nonenal citral citric acid Cintronella oil (Cymbop. Winterianus) Citronellol citronellyl acetate citroxide clary sage oil (Salvia sclarea) Clove leaf oil (Eugenia caryophyllata) cocoa-extract coffee absolut (coffea arabica) coffee extract (coffea spp.) Cognac oil, green Coriander oil (Coriandrum sativum L.) Cornmint oil (Mentha arvensis L.) Davan oil (Artemisia pallens) ,4-decadienal decanal decanol delta-damascone delta-decalactone delta-dodecalactone ,3-diethyl pyrazine dimethyl anthranilate ,5-dimethyl1,2-cyclopentandione ,3-dimethyl pyrazine ,6-dimethyl-5-heptenal ,4-dimethylphenole ,5-dimethyl pyrazine ,6-dimethyl pyrazine dimethyl sulfide D-limonene dihydrocarvyl acetate ,4-dihydrocoumarin ,5-dimethylfuran dimethyl succinate dimethoxyphenol ,5-dimeth-3-hydroxy-2,5-dihydfuran-2on diphenyl ether ,2-(dithiodimethylene)-difuran DL-isomenthone PAGE 3

4 Elemi oil (Canarium spp.) ethyl acetate ethyl acetoacetate ethyl alcohol ethyl anthranilate ethyl benzoate ethyl butyrate ethyl cinnamate ethyl decanoate ethyl-3, (5 or 6)-dimethylpyrazine / ethyl guaiacol ethyl heptanoate ethyl hexanoate ethylhexan-1-ol ethyl-4-hydroxy-5-methyl3(2H) furanone ethyl-3-hydroxy-4-methyl-2(5H) furanone ethyl isovalerate ethyl lactate ethyl laurate ethyl maltol ethyl-2-methylbutyrate ethyl-3-methylpyrazine ethyl-4-methylthiazole ethyl myristate ethyl nonanoate ethyl octanoate ethyl phenylacetate ethyl propionate ethyl salicylate ethylpyridine ethyl-trans-2-cis-4-decadienoate ethyl valerate ethyl vanillin eucalyptol Eucalyptus oil (Eucalyptus globulus) eugenol eugenol acetate fennel oil sweet (foeniculum vulgare) Fir needle oil foenugreek extract (trigonella foenu) gamma-decalactone gamma-dodecalactone gamma-heptalactone gamma-hexalactone gamma-nonalactone PAGE 4

5 gamma-octalactone gamma-terpinene gamma-undecalactone gamma-valerolactone geraniol geranyl acetate gernaly butyrate geranylisovalerate geranyl propionate glucose syrup glycerol (99.5 Pharma grade) guaiacol guaiac wood oil (Buln. Sarm/Guaiac spp.) heliotropine hexanal ,3-hexanedione ,4-hexanedione hexanoic acid hexenyl-2-methylbutanoate hexyl acetate hexyl alcohol hexyl butyrate h-5-methyl-6,7-dihydrocyclopent-pyraz hydroxy-2,5-dimethyl-3(2H)-furanone indole ionone mix (alpha- +beta-ionone) isoamyl acetate isoamyl isovalerate isoamyl butyrate isoamylnonanoate isoamyl octanoate isoamyl phenylacetate isoamyl propionate isoborynyl acetate isobutyl acetate isobutyl alcohol isobutyl butyrate isobutyl cinnamate isobutyl propionate isobutyraldehyde isobutyric acid isopropyl alcohol isopropyl-5-methyl-2-hexenal isopulegol isovaleric acid PAGE 5

6 4-ketoisophorone Labdanum oleoresin (cistus spp.) lactic acid L-carvone lauric aldhyde lauryl alcohol Lemon oil (Citrus limon) Levulinic acid Lime oil, cold pressed (Citrus aurantifol.) Limones linalool linalool oxide linalyl butyrate lovage oil (levisticum officinale) maltol massoia lactone Megastigmatrienone menthofuran menthol menthol crystals chinese menthone methoxy methyl butanethiol methoxy-3-methylpyrazine menthyl acetate methylacetophenone methyl anthranilate methyl-butan-1-ol methylbutyl acetate methylbutyraldehyde methyl butyrate methylbutyric acid methyl-1-butanol methyl cinnamate methylcoumarin methyl-1,3-cyclohexadiene methylcyclopentenolone methyl-3,4-dihydro-2-h-1-5 bezodioxepin-3-one methyl dihydrojasmonate methyl-2-hepten-6-one methyl hexanoate methyl-4-isopropenylbenzene methyl-4-isopropylidene-1-cyclohexene methyl nicotinate methyl-2-octynoate methyl-2-pentenoic acid PAGE 6

7 3-methylpentanoic acid methyl phenylacetate methyl-2-phenyl-2-hexenal methylpyrazine methyl 2-pyrrolyl ketone methylsulfinylmethane methyltetrahydrofuran-3-one methylthiazole methyl-5-thiazoleethanol methyl-2-thiofuroate (methylthio) methylpyrazine methyl-5-vinylthiazole mint lactone myrcene nonanone nerolidol neryl acetate nonenal nootkatone octanal octanoic acid octanol octanol octyl acetate olibanum oil (Boswellia spp.) omega-6-hexadecenlactone orange oil (citrus sinensis) orange oil, bitter (citrus aurantium) orange oil distilled (citrus sinensis) orange oil, sweet (citrus sinensis) paraldehyde P-cymene p-mentha-8-thiol-3-one p-menthen-4-ol pentyl acetate Peppermint oil Pepperoil black (Piper nigrum l.) perillaldehyde phenethyl acetate phenethyl alcohol phenethyl isovalerate phenethyl phenylacetate phenylacetaldehyde phenyl acetic phenylmethylbutyrate PAGE 7

8 4-(p-hydroxyphenyl)-2-butanone pinene / piperitone p-mentha-8-thiol-3-one p-menthen-4-ol p-methoxybenzaldehyde prenylacetate propenylguaethol propyl alcohol ,2 -propylene glycol USP grade propylidenephthalide p-tolylaldehyde Rosemary oil (Rosemarinus off. L.) rum (white) rumether salicylaldehyde sclareolide s-methyl thiobutanoate sorbitol Spearmint oil (Mentha spicata L.) sugar syrup inverted tetramethyl oxatricyclotridecane ,3,5,6-tetramethylpyrazine Tolu balsam trans-2-cis-6-noonadienal trans-hexen-2-al triacetin triethyl citrate ,3,5-trimethyl pyrazine ,4,5-trimethylthiazole tri-sodium citrate anhydrous undecanal valencene vanilla extract vanillin veratraldehyde Ylang ylang oil (cananga odorata) water FOR MORE INFORMATION compliance@nerudia.com OR CALL US ON +44 (0) PAGE 8

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