1 EAACI GUIDELINES ON ALLERGEN IMMUNOTHERAPY PREVENTION OF ALLERGY Supplementary materials Susanne Halken 1, Desiree Larenas-Linnemann 2, Graham Roberts 3, Moises A Calderón 4, Elisabeth Angier 5, Oliver Pfaar 6,7, Dermot Ryan 8, Ioana Agache 9, Ignacio J Ansotegui 10, Stefania Arasi 11,12, George Du Toit 13, Montserrat Fernandez-Rivas 14, Roy Gerth van Wijk 15, Marek Jutel 16,17, Jörg Kleine-Tebbe 18, Susanne Lau 12, Paolo M Matricardi 12, Giovanni B Pajno 11, Nikolaos G Papadopoulos 19,20, Martin Penagos 4, Alexandra F Santos 13, Gunter J Sturm 21, Frans Timmermans 22, Ronald van Ree 23, Eva-Maria Varga 24, Ulrich Wahn 12, Maria Kristiansen 25, Sangeeta Dhami 26, Aziz Sheikh 8, Antonella Muraro 27
AFFILIATIONS 1 Hans Christian Andersen Children s Hospital, Odense University Hospital, Odense, Denmark 2 Investigational Unit, Hospital Medica Sur, Mexico City, Mexico 3 The David Hide Asthma and Allergy Research Centre, St Mary s Hospital, Newport Isle of Wight,, NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton,, and Faculty of Medicine, University of Southampton, Southampton, 4 Section of Allergy and Clinical Immunology, Imperial College National Heart and Lung Institute, Royal Brompton Hospital, London United Kingdom 5 Department of Immunology and Allergy, Northern General Hospital, Sheffield, 6 Department of Otorhinolaryngology, Head and Neck Surgery, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, 7 Center for Rhinology and Allergology, Wiesbaden, 8 Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, ; Asthma Centre for Applied Research, The University of Edinburgh, Edinburgh, 9 Transylvania University Brasov, Faculty of Medicine, Department of Allergy and Clinical Immunology, Brasov, Romania. 10 Department of Allergy & Immunology Hospital Quironsalud Bizkaia, Erandio - Bilbao, Spain 11 Department of Pediatrics, Allergy Unit, University of Messina, Italy 12 Department for Pediatric Pneumology and Immunology, Charité Universitätsmedizin, 13 Department of Paediatric Allergy, MRC & Asthma Centre in Allergic Mechanisms of Asthma, Division of Asthma, Allergy and Lung Biology, King s College London and Guy s & St Thomas Hospital NHS Foundation trust, United Kingdom 14 Allergy Department, Hospital Clinico San Carlos, IdISSC, Madrid, Spain 15 Section of Allergology, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands; 16 Department of Clinical Immunology; Wroclaw Medical University, Poland 17 ALL-MED Medical Research Institute 18 Allergy & Asthma Center Westend, 19 Institute of Human Development, University of Manchester, 20 Allergy Department, 2nd Pediatric Clinic, University of Athens, Greece 21 Department of Dermatology and Venerology, Medical University of Graz, Graz, Austria; Outpatient Allergy Clinic Reumannplaz, Vienna, Austria 22 Nederlands Anafylaxis Netwerk - European Anaphylaxis Taskforce, Dordrecht, Netherlands 23 Departments of Experimental Immunology and of Otorhinolaryngology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands 24 Department of Pediatric and Adolescent Medicine, Respiratory and Allergic Disease Division, Medical University of Graz, Graz, Austria 25 Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark 26 Evidence Based Health Care Ltd, Edinburgh 27 The Referral Centre for Food Allergy Diagnosis and Treatment Veneto Region. Department of Women and Child Health - University of Padua. Padua, Italy
EAACI Guideline: AIT for Allergy Prevention Table S1 Details of authors Name Discipline, expertise Institution Susanne Halken Désirée Larenas- Linnemann Graham Roberts Moisés A. Calderon Elizabeth Angier Ioana Agache Ignacio J. Ansetegui Stefania Arasi George Du Toit Montserrat Fernandez- Rivas Professor, Consultant in Paediatrics and Paediatric Allergology Allergist and Pediatrician, National Investigator grade II, Head Allergy Clinic and Allergy Consultant at Hospital Médica Sur. Professor of Paediatric Allergy and Respiratory Medicine Lead for immunotherapy General Practitioner with an Interest in Allergy Associate Professor Allergy and Clinical Immunology MD, PhD. President Elect of the World Allergy Organization (WAO). Head of the Department of Allergy & Immunology Pediatrician, pediatric allergologist, metodologist, MD, PhD Consultant in Paediatric Allergy MD, PhD, Allergist, Head Allergy Department Hospital Clinico San Carlos, Associate Professor Medicine Universidad Complutense de Madrid Hans Christian Andersen Children s Hospital, Odense University Hospital Center of Excellence in Asthma and Allergy, Hospital Médica Sur The David Hide Asthma and Allergy Research Centre, St Mary s Hospital; NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust; Faculty of Medicine, University of Southampton Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London Department of Clinical Immunology and Allergy, Northern General Hospital Transylvania University Brasov, Faculty of Medicine, Department of Allergy and Clinical Immunology Department of Allergy & Immunology, Hospital Quironsalud Bizkaia Department of Pediatrics, Allergy Unit, University of Messina, Italy and Department of Pediatric Pneumology and Immunology, Charité Universitätsmedizin Berlin Division of Asthma, Allergy and Lung Biology, Department of Paediatric Allergy, MRC & Asthma Centre in Allergic Mechanisms of Asthma, King s College London; St Thomas NHS Foundation trust Allergy Department, Hospital Clinico San Carlos, IdISSC Geographical location Odense, Denmark Mexico City, Mexico Newport Isle of Wight, Southampton, Sheffield, Brasov, Romania Bilbao, Spain Messina, Italy; Madrid, Spain Description of role in guideline Member of Chairs group. Chair of EAACI AIT Guidelines Prevention Task Force. Critically reviewed draft guideline Participation online and at guideline meetings in planning and evaluating evidence and in formulating recommendations and in writing and editing of s Involved in the planning of the guideline document; critically reviewed draft guideline; coordinator of the guidelines project. Member of the prevention TF, developed approach to developing the guideline, involved in critically revising the draft gudieline. Member of chairs group. Critically reviewed, minor comments on drafts, member guideline group Review and of the Member of the Prevention TF. Reviewing and Metodologist. Participation at guideline meetings and writing and editing of s Member of the Prevention TF. Reviewing and Co-chair of the AIT guideline for IgE mediated food allergy; member of the steering committee of EAACI AIT guidelines Supplementary materials EAACI E-3
EAACI Guideline: AIT for Allergy Prevention Table S1 Continued Name Discipline, expertise Institution Roy Gerth van Wijk Marek Jutel Joerg Kleine-Tebbe Susanne Lau Paolo Maria Matricardi Giovanni B. Pajno Nikolaos G. Papadopoulos Martin Penagos Oliver Pfaar Dermot Ryan Alexandra Santos Gunter Sturm Professor of Allergology Prof. dr hab. Section of Allergology, Department of Internal Medicine, Erasmus Medical Center Wroclaw Medical University, Wroclaw, Poland; ALL-MED Medical Research Institute Geographical location Rotterdam, the Netherlands Wroclaw, Poland Professor, MD Allergy & Asthma Center Westend Professor of Pediatrics. Section Head for Pediatric Pneumology and Allergy. Senior Scientist. Head of the Molecular Allergology and Immunemodulation Working Group Professor of Pediatrics; Consultant of Pediatric Allergology Professor of Allergy & Paediatric Allergy Paediatric allergist. Clinical Researcher. Associate Professor of Otorhinolaryngology, Otorhinolaryngologist, Allergist Retired GP. Clinical Research Fellow Senior Clinical Lecturer in Paediatric Allergy Associate Profesor of Dermatology and Venerology Head Department of Pediatric Pneumology and Immunology, Charité Universitätsmedizin Molecular Allergology and Immunomodulation-Department of Pediatric Pneumology and Immunology, Charité Medical University Department of Pediatrics, Allergy Unit, University of Messina Institute of Human Development, University of Manchester, Manchester, ; Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece Section of Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College Royal Brompton Hospital Department of Otorhinolaryngology, Head and Neck Surgery, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University; Center for Rhinology and Allergology Usher Institute of Population Health Sciences and Informatics, University of Edinburgh Medical School Department of Paediatric Allergy, Division of Asthma, Allergy and Lung Biology, King s College Guy s and St Thomas Hospital NHS Foundation Trust Department of Dermatology and Venerology, Medical University of Graz; Outpatient Allergy Clinic Reumannplatz Messina, Italy Manchester, ; Athens, Greece Mannheim, Wiesbaden, Edinburgh, Vienna, Austria Description of role in guideline Member chairs group, chair primary care & health economics, conception, drafting, revising and of papers Member of chairs group. Reviewing and Member of the Prevention TF. Reviewing and Chair of Asthma Guideline TF. Participation at guideline meetings and writing and editing of s Critical reviewing and Member of Chairs Group. Chair of EAACI AIT Food Allergy Task Force Guidelines Member of EAACI AIT Guidelines Prevention Task Force. Critically reviewed draft guideline Reviewing and Participation at guideline meetings and reviewing the s. Member of Prevention TF; member of Chairs group; Cochair of ARC-TF; participation at TF-meetings; reviewing, editing and final of Reviewing and Review and of the Member of chairs group. Review and of the E-4 EAACI Supplementary materials
EAACI Guideline: AIT for Allergy Prevention Table S1 Continued Name Discipline, expertise Institution Frans Timmermans Eva-Maria Varga Ulrich Wahn Ronald van Ree Maria Kristiansen Sangeeta Dhami Aziz Sheikh Antonella Muraro Health, Safety, Environment and Quality Consultant and acting as Secretary General of NAN/EAT Associate Professor of Paediatrics; Consultant Paediatric Pulmonologist and Allergist Prof. Dr. med. Chief Editor, Pediatric Allergy and Immunology Professor of Molecuar and Translational Allergology Associate professor of health services research GP, Director of Evidence Based Health Care Ltd Professor of Primary Care Research & Development and Consultant Paediatric Allergist Professor of Pediatric Allergy_Head of the Food Allergy Referral Centre Department of Women and Child Health Nederlands Anafylaxis Netwerk European Anaphylaxis Taskforce Department of Pediatric and Adolescent Medicine, Respiratory and Allergic Disease Division, Medical University of Graz Department for Ped Pneumology and Immunology, Charite Departments of Experimental Immunology and of Otorhinolaryngology, Academic Medical Center, University of Amsterdam Section for Health Services Research, Department of Public Health, University of Copenhagen Evidence-Based Health Care Ltd Asthma Centre for Applied Research, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh Medical School Department of Mother and Child Health, The Referral Centre for Food Allergy Diagnosis and Treatment Veneto Region, University of Padua All authors fulfil the international and EAACI authorship criteria Geographical location Dordrecht, the Netherlands Graz, Austria Amsterdam, the Netherlands Copenhagen, Denmark Edinburgh, Edinburgh, Padua, Italy Description of role in guideline Critically reviewed, minor comments on drafts, member guideline group Chair Venom TF;TF-Member AR-TF. Review and of the Review and of the Conception, drafting, reviewing, Methodologist and contributing to the editing of the manuscrupt. Methodologist. Involved in carrying out the systematic review and cross-checking evidence in guidelines Lead methodologist and contributing to the writing and editing of the Chair of the Guidelines project; involved in the planning of the guideline document; critically reviewed draft guideline. Review and of the Supplementary materials EAACI E-5