ChromaDex Tea Services

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1 ChromaDex Tea Services setting THE standard

2 2 ChromaDex Tea

3 Introduction ChromaDex has established a Tea Services Division to meet the complex needs of a rapidly changing global tea industry. In the USA alone, sales of tea beverages have skyrocketed from sales of less than $1 billion dollars annually in 1990 to an estimated $6.8 billion in Forecasts point towards sales topping $10 billion in the next two years (USA). Sales of consumer products containing tea as an ingredient now outnumber beverage teas sold worldwide. Yet, in spite of the desirable increase in demand for tea products, especially specialty tea oriented, a number of factors are adding extra pressure to the otherwise stellar industry growth patterns; intense competitor, regulatory and producing origin actions are shaking up the tea business landscape. ChromaDex Tea Services are modeled after our successful natural products industry divisions which have productively served companies within the dietary supplement (nutraceutical), food and beverage, cosmetic, and pharmaceutical sectors for many years. Whether your tea company, product or technology needs basic analytical services or comprehensive research and development support, ChromaDex Tea Services can assist your team as required. Introduction 3 Tea Average Data 5 Understanding ORAC & Folin C 7 Reference Standards and Materials (CRM and BRMs) 8 Analytical Services 10 HPLC for purity/potency Metals Microbiology Pesticides ORAC Tea Verification Program 13 Research and Development Services 15 Product development Ingredient development Litigation, Merger & Aquisition Support 17 Tea Ingredients Annual and Tea is HOT report 18 Contact ChromaDex Muirlands Blvd., Suite G Irvine, CA Phone: Fax: sales@chromadex.com Services sales@chromadex.com 3

4 4 Tea Analysis Ave

5 Tea Analysis Averages ChromaDex has developed a tea analysis method for the specified compounds below. Several of the basic tea types have been tested during an internal study which has generated a basic set of averages for each tea type as an 8 oz. cup of tea. Additional testing programs will create a viable baseline model for the various tea regions around the world. Method of Analysis: HPLC with UV detector Analysis for: 1. Catechins: a. (+)-Catechin b. (-)-Epicatechin c. (-)-Epicatechin gallate d. (-)-Epigallocatechin e. (-)-Epigallocatechin gallate 2. Theaflavins: a. Theaflavin b. Theaflavin-3-gallate c. Theaflavin-3 -gallate d. Theaflavin-3,3 -digallate 3. Xanthines: a. Caffeine b. Theophylline c. Theobromine For further details about the ChromaDex Tea Services test method, please Contact our technical sales department at: sales@chromadex.com (949) setting THE standard Type Average Catechins Average Caffeines Average Theaflavins White 12.58% 2.71% 0.10% White Decaf 11.93% 0.44% 0.04% Green 11.38% 2.26% 0.05% Green Decaf 11.48% 0.48% 0.05% Black 5.50% 3.22% 0.67% Black Decaf 4.14% 0.70% 0.61% Values are presented in % per 8 oz. cup of tea. rages sales@chromadex.com 5

6 ChromaDex 6 Products and Se

7 Understanding ORAC & Folin C % Folin-C vs. HPLC White Green Green Black Black % Polyphenol Content ORAC and Folin C are nonspecific anaylsis methods HPLC IS a specific analysis method ORAC and Folin C values can not be compared from one product to another. HPLC values CAN be compared ORAC and Folin C values do not determine actual content of individual antioxidants in a tea product HPLC values DO determine actual content of individual antioxidants ORAC and Folin C values do not indicate the biological value of antioxidants HPLC CAN determine the content of biologically active antioxidants Ask us about our Single Lab Validation program for tea analysis by HPLC and how you can be part of setting the tea industry standard for excellence! For more information: Call (949) or info@chromadex.com rvices sales@chromadex.com 7

8 Reference standards an Main Tea Catechins Tea Related Standards Product ID Product Name Qty/ Unit Price* ASB (+)-CATECHIN (AHP) 10mg ASB (+)-CATECHIN (AHP) 25mg ASB (-)-EPICATECHIN (AHP) 5mg ASB (-)-EPICATECHIN (AHP) 10mg ASB (-)-EPICATECHIN (AHP) 25mg ASB (-)-EPICATECHIN (AHP) 50mg ASB (-)-EPICATECHIN GALLATE (P) 5mg ASB (-)-EPICATECHIN GALLATE (P) 10mg ASB (-)-EPICATECHIN GALLATE (P) 25mg ASB (-)-EPIGALLOCATECHIN (P) 10mg ASB (-)-EPIGALLOCATECHIN (P) 25mg ASB (-)-EPIGALLOCATECHIN (P) 50mg ASB (-)-EPIGALLOCATECHIN GALLATE (P) 5mg ASB (-)-EPIGALLOCATECHIN GALLATE (P) 10mg ASB (-)-EPIGALLOCATECHIN GALLATE (P) 25mg ASB (-)-EPIGALLOCATECHIN GALLATE (P) 50mg Other Tea Related Catechins Product ID Product Name Qty/ Unit Price* ASB (-)-CATECHIN (RG) 5mg ASB DL-CATECHIN (SH) 10mg ASB DL-CATECHIN (RG) 10mg ASB DL-CATECHIN (RG) 100mg ASB (-)-CATECHIN GALLATE (SH) 5mg ASB (-)-CATECHIN GALLATE (SH) 10mg ASB (-)-EPIGALLOCATECHIN GALLATE (RG) 1g ASB (-)-EPIGALLOCATECHIN GALLATE (RG) 5g ASB (-)-GALLOCATECHIN (SH) 5mg ASB (-)-GALLOCATECHIN GALLATE (SH) 5mg Black Tea Theaflavins Product ID Product Name Qty/ Unit Price* ASB THEAFLAVIN (P) 10mg ASB THEAFLAVIN (P) 5mg ASB THEAFLAVIN-3-GALLATE (SH) 10mg ASB THEAFLAVIN-3-GALLATE (SH) 5mg ASB THEAFLAVIN-3,3 -DIGALLATE (P) 10mg ASB THEAFLAVIN-3,3 -DIGALLATE (P) 5mg sales@chromadex.com

9 d materials (CRMs and BRMs) Caffeine Related Compounds (Xanthine Alkaloids) Product ID Product Name Qty/ Unit Price* ASB CAFFEINE (P) 100mg ASB CAFFEINE (P) 200mg ASB THEOBROMINE (P) 100mg ASB THEOBROMINE (P) 200mg ASB THEOPHYLLINE (P) 100mg ASB THEOPHYLLINE (P) 100mg Other Related Tea Compounds of Interest Product ID Product Name Qty/ Unit Price* ASB GALLIC ACID (P) 10mg ASB GALLIC ACID (P) 100mg ASB GALLIC ACID (P) 1g ASB L-THEANINE (P) 10mg ASB L-THEANINE (P) 25mg Botanical Reference Materials (BRMs) Product ID Product Name Qty/ Unit Price* ASB GREEN TEA LEAF vbrm 5g Tea Related Analysis Kits Product ID Product Name Qty/ Unit Price* KIT GREEN TEA CATECHIN STANDARDS KIT 5 x 10mg KIT GREEN TEA CATECHIN STANDARDS KIT 5 x 25mg KIT HK GREEN TEA CATECHIN HPLC ANALYSIS KIT 1 kit KIT HK GREEN TEA CATECHIN HPLC KIT w/ GRD COL 1 kit KIT BLACK TEA THEAFLAVIN STANDARDS KIT 3 x 10mg KIT BLACK TEA THEAFLAVIN STANDARDS KIT 3 x 5mg CALL BLACK TEA THEAFLAVIN HPLC ANALYSIS KIT 1 Kit To order contact a ChromaDex representative today (949) or sales@chromadex.com Visit sales@chromadex.com 9

10 Analytical Servic Tea Phyto-Constituents Polyphenol Content for All Camellia sinensis (Black Tea, White Tea, Green Tea, Oolong Tea, Puerh Tea) Description Report Type 1 Sample 2-4 Samples 5-9 Samples 10+ Samples Service Code Polyphenol Content (Total) by Folin C ARS CDA ARS Polyphenol Content (Total) by Folin C ATR CDA ATR Tea for Catechins by HPLC ARS CDA ARS Tea for Catechins by HPLC ATR CDA ATR Tea for Theaflavines by HPLC ARS CDA ARS Tea for Theaflavines by HPLC ATR CDA ATR Tea Total Polyphenol Content by HPLC ARS CDA ARS Tea Total Polyphenol Content by HPLC ATR CDA ATR Caffeine Content (Xanthine Alkaloids) Description Report Type 1 Sample 2-4 Samples 5-9 Samples 10+ Samples Service Code Caffeine (Xanthine Alkaloids) Analysis by HPLC ARS CDA ARS Caffeine (Xanthine Alkaloids) Analysis by HPLC ATR CDA ATR Tea Identity Testing Description Report Type 1 Sample 2-4 Samples 5-9 Samples 10+ Samples Service Code Green Tea Leaf (Camellia sinensis) Identity Testing by HP-TLC ARS CDA ARS Green Tea Leaf (Camellia sinensis) Identity Testing by HP-TLC ATR CDA ATR Black Tea Leaf (Camellia sinensis) Identity Testing by HP-TLC ARS CDA ARS Black Tea Leaf (Camellia sinensis) Identity Testing by HP-TLC ATR CDA ATR Rooibos (Aspalathus linearis) Identity Testing by HP-TLC ARS CDA ARS Rooibos (Aspalathus linearis) Identity Testing by HP-TLC ATR CDA ATR Tea Identity Testing by Bioluminex ARS CDA ARS Tea Identity Testing by Bioluminex ATR CDA ATR Microbiological Testing Contaminants Testing Description Report Type 1 Sample 2-4 Samples 5-9 Samples 10+ Samples Service Code FULL MICROBIOLOGICAL PANEL #1 ARS CDA ARS FULL MICROBIOLOGICAL PANEL #2 ARS CDA ARS FULL MICROBIOLOGICAL PANEL #3 ARS CDA ARS FULL MICROBIOLOGICAL PANEL #4 ARS CDA ARS TOTAL AEROBIC COUNT ARS CDA ARS TOTAL YEAST AND MOLD PANEL ARS CDA ARS sales@chromadex.com

11 es - Tea Testing Microbiological Testing Contaminants Testing Description Report Type 1 Sample 2-4 Samples 5-9 Samples 10+ Samples Service Code COLIFORM ARS CDA ARS E. COLI ARS CDA ARS ENTEROBACTERIACEAE ARS CDA ARS PSEUDOMONAS ARS CDA ARS LISTERIA ARS CDA ARS SALMONELLA ARS CDA ARS STAPHYLOCOCCUS AUREUS ARS CDA ARS E. COLI 0157:H7 ARS CDA ARS Metals Description Report Type 1 Sample 2-4 Samples 5-9 Samples 10+ Samples Service Code RCRA 8 Metals Panel by ICP ARS CDA ARS Metal Testing: Arsenic analysis by ICP ARS CDA ARS Metal Testing: Cadmium analysis by ICP ARS CDA ARS Metal Testing: Chromium analysis by ICP ARS CDA ARS Metal Testing: Copper analysis by ICP ARS CDA ARS Metal Testing: Iron analysis by ICP ARS CDA ARS Metal Testing: Lead analysis by ICP ARS CDA ARS Metal Testing: Magnesium analysis by ICP ARS CDA ARS Metal Testing: Manganese analysis by ICP ARS CDA ARS Metal Testing: Mercury analysis by ICP ARS CDA ARS Metal Testing: Molybdenum analysis by ICP ARS CDA ARS Metal Testing: Potassium analysis by ICP ARS CDA ARS Metal Testing: Selenium analysis by ICP ARS CDA ARS Metal Testing: Zinc analysis by ICP ARS CDA ARS Pesticides Description Report Type 1 Sample 2-4 Samples 5-9 Samples 10+ Samples Service Code Pesticide Screening Panel CDFA ARS CDA ARS ORAC/Biological Assays Description Report Type 1 Sample 2-4 Samples 5-9 Samples 10+ Samples Service Code ORAC Hydrophyllic and Lipophyllic Assay ATR CDA ATR Bioactivity Fingerprint Testing by Bioluminex ARS CDA ARS Bioactivity Fingerprint Testing by Bioluminex ATR CDA ATR sales@chromadex.com 11

12 Analytical Services - Tea Testing Amino Acids Other Tea Nutrient Testing Description Report Type 1 Sample 2-4 Samples 5-9 Samples 10+ Samples Service Code L-Theanine Analysis by HPLC ARS CDA ARS L-Theanine Analysis by HPLC ATR CDA ATR Note: Other amino acids are available upon request Vitamins Description Report Type 1 Sample 2-4 Samples 5-9 Samples 10+ Samples Service Code Vitamin A (Retinol) by HPLC ARS CDA ARS Vitamin A (Retinol) by HPLC ATR CDA ATR Vitamin B Panel by HPLC ARS CDA ARS Vitamin B Panel by HPLC ATR CDA ATR Vitamin B1(Thiamine) by HPLC ARS CDA ARS Vitamin B1(Thiamine) by HPLC ATR CDA ATR Vitamin B12 (Cyanocobalamin) by HPLC ARS CDA ARS Vitamin B12 (Cyanocobalamin) by HPLC ATR CDA ATR Vitamin B12 Analysis by HPLC ATR CDA ATR Vitamin B2 (Riboflavin) by HPLC ARS CDA ARS Vitamin B2 (Riboflavin) by HPLC ATR CDA ATR Vitamin B3 (Niacinamide) by HPLC ARS CDA ARS Vitamin B3 (Niacinamide) by HPLC ATR CDA ATR Vitamin B5 (Calcium Pantothenate) by HPLC ARS CDA ARS Vitamin B5 (Calcium Pantothenate) by HPLC ATR CDA ATR Vitamin B6 (Pyridoxine) by HPLC ARS CDA ARS Vitamin B6 (Pyridoxine) by HPLC ATR CDA ATR Vitamin C (Ascorbic Acid) by HPLC ARS CDA ARS Vitamin C (Ascorbic Acid) by HPLC ATR CDA ATR Vitamin C (Ascorbic Acid) Full Panel by HPLC ARS CDA ARS Vitamin D2 (Ergocalciferol - formula) by HPLC ARS CDA ARS Vitamin D2 (Ergocalciferol - formula) by HPLC ATR CDA ATR Vitamin D3 (Cholecalciferol - formula) by HPLC ARS CDA ARS Vitamin D3 (Cholecalciferol - formula) by HPLC ATR CDA ATR Vitamin E (Tocopherols) by HPLC ARS CDA ARS Vitamin E (Tocopherols) by HPLC ATR CDA ATR Tocopherol (Vitamin E) by HPLC ARS CDA ARS Tocopherol (Vitamin E) by HPLC ATR CDA ATR Folic Acid (Vitamin M) (w/sample clean up) by HPLC ARS CDA ARS Folic Acid (Vitamin M) (w/sample clean up) by HPLC ATR CDA ATR Biotin - formula (w/sample clean up) by HPLC ARS CDA ARS Biotin - formula (w/sample clean up) by HPLC ATR CDA ATR sales@chromadex.com

13 Tea Verification Programs ChromaDex will soon offer a comprehensive range of verification services, where tea related businesses can send samples of their tea products of several different types for origin, purity, and potency verification. ChromaDex will start with the launch of Polyphenol Content Verified and Decaffination Verified. POLYPHENOL CONTENT VERIFIED DECAFFEINATION VERIFIED After the launch of the first two verification services above we will launch programs including Verified Contaminant Free to help companies build confidence in consumers that their products are free of heavy metals, pesticides and microbiological contamination. ChromaDex is also working on a program to verify the geo-origin of different types of tea. CONTAMINANT FREE VERIFIED IDENTITY VERIFIED For more information about these new verification programs, or if you would like to become part of the ChromaDex Verification Services programs please contact us at sales@chromadex.com 13

14 Research 14 and Developmen

15 Research and Development Services The ChromaDex Tea Services offers turnkey analytical and R&D support resources for virtually any type of tea (or herbal tea ) ingredient, product or technology. Our team of experts brings decades of both analytical sciences and tea industry experience to all of your projects. From simple product R&D support to complex initiatives, ChromaDex provides an unparalleled range of tea ingredient (raw or processed raw materials), products (finished goods) and technology (processing, brewing, dispensing) R&D services to clients located all over the world. Our Tea Services include constituent isolation, product formulation (original and updates) and process development, through bioassay services and comprehensive consulting. All ChromaDex Tea Services are centered on our successful client service models used to service clients in the natural products industry. Ideation: Creative concepts (tea products or targeted demographics, niche segments, product / brand revitalization Product formulation, updates and troubleshooting Organoleptic (Sensory) Assessments: Blind cupping assessments by skilled tea industry veterans, formal tasting panels and product profiling Product Assessments: Competitor differentiation and positioning analysis Flavor Support: Simple and complex flavoring of dry, liquid and other tea materials, novel flavors (natural, organic applicable, artificial) Specimen Verification, Botanical Reference Standards (Tea & Herbal Tea) Archive Libraries, Origin Authenticity Documentation, Origin Characterization Profiling Quality Assurance Systems, Labeling Programs & Testing for Individual Products, Trade Associations, Producing Origins t Services sales@chromadex.com 15

16 Litigation, 16 Merger & Aquisit

17 Litigation, Merger & Aquisition Support Whether you are utilizing tea within a beverage, dietary supplement, food, cosmetic or other application, manufacturing processes, formulations and marketing materials periodically need to be assessed for quality and marketing claims. ChromaDex can offer true end-to-end analytical services to enhance litigation prevention as well as support companies during litigation. ChromaDex has performed litigation support such as: Product content and label claims Product adulteration Expert witness for analytical or quality issues False advertising claims related to product content Raw material, contract manufacturing disputes Patent infringement Mediation where analytical data is in question Merger & Aquisition Services Technology transfer support Merger & Acquisition due diligence support (materials, products, technologies) Product testing, patent searches and expert opinion prior to Merger & Acquisition closure Active tea-focused Merger & Acquisition, tech-transfer referrals and introductions Risk Managment Insurance rate reduction Reduce potential litigation exposure ion Support sales@chromadex.com 17

18 Tea Ingredients Annual 2008 TEA INGREDIENTS ANNUAL 2008 TheÊ UltimateÊ TeaÊ ProductsÊ IngredientsÊ Directoryª Insider Sources: Extracts, Concentrates, Essences, Flavorings, Nutraceutical & Functional Additives Analytical Testing Laboratories with Tea-Specific Services Resources for manufacturers, formulators, food technologists: Beverage, Skincare, Pharma & More Tools for Navigating An Emerging Marketplace...& More Publishing Relevant Tea Industry Information, Resources & Insights Since Denver, Colorado / USA Tea Ingredients Annual 2008 Tea-based ingredients are becoming the number one choice for adding innovation and health to diverse consumer products. TIA 2008 is the ultimate source-book for companies manufacturing products containing tea-based ingredients; a must-have resource for formulators, food technologists and consumer product scientists. TIA lists ingredient suppliers (tea and herbal tea), analytical laboratories and detailed information on scientifically assessing tea-based ingredients. Visit to p 18

19 Tea is HOT Report Specialty Tea Is Hot Report 6th Edition provides a vital snapshot of the US specialty tea industry and key market catalysts, as well as, tea trends, fads circa Includes a retailer pricing (products) survey and supply chain quantification. Find information on the art and science of professional tea tasting, the aroma of tea, Fair Trade and specialty tea value propositions, insights and opinions. Learn how to buy, analyze and store tea from the world s leading experts. Tea Is Hot Report 5th Edition provides a vital snapshot of the US specialty tea industry, circa the early 2000s. Including close-up coverage on Decaffeinated tea, Organic, Fair Trade, Chai, Herb Tea and Yerba Maté and information on key tea producing origins, with commentary, data and profiles. This edition provides the very first retailer quantification estimates, as well as coverage on tea extracts, tea and health and other nonbeverage tea topics not covered anywhere else. urchase these publications 19

20 Muirlands Blvd., Suite G Irvine, CA RETURN SERVICE REQUESTED 04/2010

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