UBIC THE WORLD CASEIN & CASEINATES MARKET CONSULTING. Marketing development Strategy consulting Partnership searches Information systems

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Science Market Regulation UBIC 2015 Marketing development Strategy consulting Partnership searches Information systems

Technical & Competitive Scanning Regulations Manufacturers This comprehensive report is based on in-depth interviews with food companies completed by a desk review. It provides for DECISION MAKERS a global understanding of the sector as well as an outlook on its future. MARKET ANALYSIS Trends and Outlook Use of ingredients: volumevalue Manufacturers profiles Users opinions Regulation MARKET COVERED North America Western Europe Asia Australia- New Zealand APPLICATIONS Food Industry Functional food Food supplements Sports food Industrial markets Clinical nutrition INGREDIENTS COVERED Casein Caseinates Casein hydrolysates

O B J E C T I V E S M A R K E T Food consumption trends and expectations Consumer market trends by food segments Prospective INTRODUCTION Casein is the main protein found in milk and contains 21 amino acids. It makes up approximately 80 % of the total milk protein. Above all, casein is a source of several functional peptides with different properties for instance nervous system and body's fortification (see below), behavior, intestinal comfort, cardiovascular system Caseins and caseinates are widely used in the food and non-food industry where they provide functional benefits of structure formation, emulsification, water binding, foaming, viscosity and heat stability. Casein may be processed in view of being transformed at a later stage as caseinates as they are not soluble. As a consequence, casein appears frequently in statistics in place of caseinates. This is the case for applications like sports nutrition, infant formula or even Clinical nutrition. M A N U F A T U R E R S Food industry orientations Opioid activity Satiety Biotransfer of calcium Antimicrobial activity Applications in food segments Consumption R E S E A R C H New researches and new developments Both whey and casein can boost the protein content of the food without a decline in taste. Studies examining the effects of the dairy proteins whey and casein on appetite regulation have been conducted through the National Centre of Excellence in Functional Foods. These studies suggest that both proteins exert appetite suppressant effects compared to an isocaloric glucose load and similar to a low GI Carbohydrates (lactose) load.

O B J E C T I V E S M A R K E T Food consumption trends and expectations Consumer market trends by food segments Prospective M A N U F A T U R E R S Food industry orientations Applications in food segments Consumption R E S E A R C H New researches and new developments OUTLOOK OF THE MARKET Caseins and caseinates are widely used in the food and non-food industry where they provide functional benefits of structure formation, emulsification, waterbinding, foaming, viscosity and heat stability. The demand for casein is important in companies of milk products such as powder cream for coffee bleaching and infantile powders. However, the use of food casein (lactic casein) in foodstuff has decreased. It is replaced by more recent ingredients (others protein milk derivatives like Total Milk Proteins, vegetal proteins ). Nevertheless the fall has stabilized today and new prospective are coming with applications as raw material used for functional food or food supplements. Caseins are employed mainly in: Dietary preparations: Infant foods (fortification infant foods) Pharmaceutical products Caseinates more usually used in the food are the sodium caseinates, less expensive and more soluble. They are highly soluble and have excellent emulsifying and whipping properties. They are used extensively in the manufacture of coffee whiteners, whipped toppings, cream liqueurs, yogurt, processed cheeses and meat products. Europe is the largest market for casein and caseinates. World demand for caseins and caseinates in the nutraceutical market is difficult to estimate. According to several interviews of industrial users, it would be close to 000 tons in 2014. The world market for industrial casein is estimated between 000 000 tons in 2014. Development of a continuous process to make films from specialty casein and casein fractions. Some of the players in the casein and caseinates market : American Casein Company, Erie Casein Company Inc Fonterra, Gansu Hualing Milk Products Group, Kerry Ingredients, Lactalis and Casein India among many others. Share of casein and caseinates production by country 2014 Rest of Europe Denmark Ireland France Germany

O B J E C T I V E S M A R K E T CASEIN APPLICATIONS MARKET SIZE Food consumption trends and expectations Consumer market trends by food segments Technical applications of caseins and caseinates Market and volume Product Property Application s Coating Remarks Examples Volume used Prospective M A N U F A T U R E R S Food industry orientations Adhesive Plastic Applications in food segments Surfactant Consumption R E S E A R C H New researches and new developments United States EU ROW - Japan World market 2014 Total market Market for health applications

TABLE OF CONTENT 1.INTRODUCTION 11 CASEIN & CASEINATE GENERALITIES 12 PRODUCT DESCRIPTION 13 RENNET CASEIN 17 CASEIN 17 CASEINATES 17 MICELLAR CASEIN CONCENTRATES (MCC) 17 2.CASEIN SCIENTIFIC AND TECHNICAL SCAN 20 TECHNOLOGICAL PROPERTIES 21 PH STABILITY OF CASEINS AND CASEINATES 21 COAGULATION OF CASEINS 21 ENZYME COAGULATION 21 ACID COAGULATION 21 HEAT 21 AGE GELATION 21 SOLUBILITY OF CASEINS AND CASEINATES 22 FAT BINDING OF CASEINS AND CASEINATES 22 NUTRITIONAL PROPERTIES 23 NUTRACEUTICAL PROPERTIES 23 CASEIN FRACTIONS AS BIO-ACTIVE PEPTIDES 25 BIOACTIVE FUNCTIONS 26 NERVOUS SYSTEM AND BEHAVIOR 26 INTESTINAL CONFORT 26 BODY S DEFENSE 26 IMMUNOMODULATORY EFFECT 26 ANTIMICROBIAL EFFECT 26 CARDIOVASCULAR SYSTEM 27 BODY S FORTIFICATION 27 GLYCOMACROPEPTIDE 28 NUTRACEUTICAL PROPERTIES 28 NERVOUS SYSTEM AND BEHAVIOUR 28 BODY S DEFENSE 28 VASCULAR SYSTEM 28 INTESTINAL CONFORT 28 DIGESTIVE PHYSIOLOGY 29 ANTI CARIOGENIC PROPERTIES 29 CURRENT AND POTENTIAL APPLICATIONS 30 CPP ( CASEIN PHOSPHO PEPTIDE) 30 NUTRACEUTICAL PROPERTIES 30 CURRENT AND POTENTIAL APPLICATIONS 30 3.PROCESS 32 ISOLATION METHODS 33 MANUFACTURE OF CASEIN 34 MANUFACTURE OF CASEINATE 35 MANUFACTURE OF CO-PRECIPITATE 36 4.STRATEGIC ASSESSMENT 37 INCREASED GLOBALISATION OF DAIRY INDUSTRY 38 NEED FOR DAIRY PRODUCTS 39 SUPPLIERS FUTURE COMMERCIAL POLICY 39 FUTURE NET IMPORTERS OF DAIRY GOODS 40 CHINA & SOUTH EAST ASIA 40 INDIA 41 JAPAN 41 RUSSIA 42 REST OF THE WORLD 42

5.MARKET DESCRIPTION AND DATA BY SEGMENTS 44 CASEIN AND CASEINATE MARKET 45 PROTECTED APPLICATIONS 46 INDUSTRIAL APPLICATIONS 47 APPLICATION IN THE FOOD INDUSTRY 48 FUTURE OPPORTUNITIES FOR CASEIN IN FUNCTIONAL FOOD 49 APPLICATION IN DAIRY & CHEESE PRODUCTS 50 APPLICATION IN MEAL REPLACEMENT 50 APPLICATION IN CONFECTIONERY 50 APPLICATION IN BAKERY PRODUCTS AND SNACKS 50 APPLICATION IN SOUPS AND PASTA 51 APPLICATION IN MEAT PRODUCTS 51 APPLICATION IN CLINICAL NUTRITION 51 APPLICATION IN NUTRITIONAL BEVERAGES 52 APPLICATION IN SPORTS & SLIMMING FOOD 52 APPLICATION IN INFANT NUTRITION 53 6.MARKET DATA BY COUNTRY 56 WORLD MARKET 57 UNITED-STATES 59 IMPORTS OF CASEIN 62 IMPORTS OF CASEINATES 63 EXPORT OF CASEIN 65 EXPORT OF CASEINATES 66 INDUSTRIAL CASEIN EXPORT 67 INDUSTRIAL CASEIN IMPORT 67 IMPORTS FROM NEW ZEALAND 68 PRICES OF EDIBLE CASEIN 68 CANADA 72 SOUTH AMERICA (MEXICO, BRAZIL, CHILE, VENEZUELA, ARGENTINA) 75 MEXICO 75 BRAZIL 76 CHILE 77 ARGENTINA 81 VENEZUELA 81 EUROPE 81 EUROPEAN PRICES 81 EUROPEAN UNION: PRODUCTION OF CASEIN/ CASEINATES 83 SHARE OF IRELAND 87 IMPORTS/EXPORTS OF CASEIN/CASEINATES 88 FRANCE 89 GERMANY 90 POLAND 91 THE NETHERLANDS 93 IRELAND 94 DENMARK 95 COMMUNITY OF INDEPENDENT STATES (RUSSIA, UKRAINE, BELARUS) 96 RUSSIA 96 UKRAINE 96 BELARUS 97 OCEANIA (AUSTRALIA, NEW ZEALAND) 98 AUSTRALIA 98 NEW ZEALAND 100 ASIA (JAPAN, INDIA, CHINA, SINGAPORE) 103 JAPAN 103 INDIA 103 CHINA 106 SINGAPORE 108 KOREA 110 THAILAND 111 MALAYSIA 112

7.MARKET CONCLUSIONS & FORECASTS 114 FORECAST FOR THE CASEIN MARKET 114 OUTLOOK 116 SYNOPSIS OF WORLD TRADES OF CASEIN/ CASEINATES 117 SYNOPSIS OF INTRA-EU TRADES OF CASEIN/ CASEINATES 118 8.CASEIN USERS 119 EUROPE 120 ADAMS FOOD (IRISH DAIRY BOARD- UK) 123 MOLKEREI ALOIS MULLER GMBH (G) 125 DANONE (F) 130 ELSA SA (CH) 134 FRIESLAND CAMPINA GERMANY (G) 136 FRIESLAND CAMPINA (NL) 137 NESTLE (CH) 139 ABBOTT NUTRITIONALS (ESP) 142 SODIAAL (F) 148 VALIO (FIN) 149 HOCHDORF SWISS MILK COMPANY (CH) 151 MILUPA (NUMICO GROUP - G) 152 ARKOPHARMA (F) 153 SHANNON MINERALS (IRL) 153 HEINZ (UK) 155 CAMPOFRIO ALIMENTACION (SP) 157 HERTA (F) 162 KARL KONECKE (G) 163 GROUPE FLEURY MICHON (F) 164 MAIZENA (G) 165 USA BARIATRIX (CDN ) 167 GENERAL MILLS (USA) 170 KRAFT (USA) 174 KOHLER MIX (USA) 179 MEAD JOHNSON (USA) 181 JOE WEIDER NUTRITION (USA) 185 NABISCO BISCUITS (USA) 186 9.CASEIN MANUFACTURERS 189 EUROPE 190 ARMOR PROTEINES (F) 190 LACTALIS (F) 195 FRIESLAND CAMPINA (NL) 199 INTERNATIONAL DAIRY INGREDIENTS (EURIAL INGREDIA) (F) 204 LACTOPROT (G) 208 EPI INGREDIENTS (F) 210 MGL FOOD INGREDIENTS (G) HOCHDORF GROUP (CH) 213 SACHSEN MILCH - MOLKEREI LEPPERSDORF ERIE CASEIN COMPANY INC (USA 215 AMERICAN CASEIN COMPANY 217 MILK SPECIALTIES INC. (USA) 219 MEXICO 220 LACTE DU MONDE SA, DE CV (MX) 220 DILAC SA, DE CV (MX) 221 CHINA 222 GANSU HUALING MILK PRODUCTS GROUP 222 KERUI DAIRY 223 LANZHOU LONGRUAN CASEIN CO LTD 224 INDIA 225 BHOLE BABA DAIRY INDUSTRIES 225 DYNAMIX DAIRY INDUSTRY LTD (SCHRIBER FOODS USA) 227 CASEIN INDIA 227 CHAROTAR INDIA 228 VENUS CASEIN PRODUCTS 228 CLARION CASEIN PVT LTD 229 INDIAN CASEIN INDUSTRIES 229 MAHAAN LTD (IND) 230 OCEANIA 234 WESTLAND MILK PRODUCTS (NZ) 234 FONTERRA (NZ) 237 TATUA (NZ) 242

10.REGULATIONS AND CASEIN IMPORTERS 244 ASIA 244 SINGAPORE 245 HONG KONG 246 KOREA 253 THAILAND 256 CHINA 257 TAIWAN 258 THE PHILIPPINES 259 MALAYSIA 260 JAPAN 260 OCEANIA 261 AUSTRALIA 261 NORTH AMERICA 265 UNITED STATES 261 U.S. CASEIN IMPORTERS 261 AGRI DAIRY PRODUCTS 265 JLS FOODS INTERNATIONAL 266 EUROPROTEINS 268 CANADA 269 SOUTH AMERICA 274 PERU 274 GUATEMALA 274 HONDURAS 275 SALVADOR 275 NICARAGUA 275 PANAMA 275 ARGENTINA 276 CHILE 278 MEXICO 279 BOLIVIA 281 COSTA RICA 284 BRAZIL 284 MIDDLE EAST 284 BAHRAIN 284 SAUDI ARABIA 284 AFRICA 286 SENEGAL 286 SOUTH AFRICA 287 EUROPEAN UNION 288 EU REGULATION 288 GREECE 288 THE NETHERLANDS 288 HAVERO HOOGWEGT 289 INTERFOOD BV 290 MELKWEG HOLLAND BV 291 NAARDEN AGRO PRODUCTS 292 BELGIUM 295 FRANCE 295 UNIPEX 295 POLAND 297 RUSSIA 298

LISTE OF TABLES TABLE 1. DISTRIBUTION OF CASEINS OF COW S MILK (%, WET MATTER) 16 TABLE 2. COMPOSITION IN AA RESIDUS FOR 6 MAJOR PROTEINS OF COW S MILK 16 TABLE 3.THE VARIOUS TYPES OF MILK INGREDIENTS 18 TABLE 4. CASEIN HEALTH APPLICATIONS 19 TABLE 5. NUTRITIONAL VALUE OF CASEIN 23 TABLE 6. AMINO-ACID CONTENT OF SODIUM CASEINATES USED IN PROCESSED FOODS (%) 23 TABLE 7. CASEIN - NUTRACEUTICAL PROPERTIES 24 TABLE 8. COMPARATIVE REDUCTION OF CARIES WITH FORMULA USING CGMP 29 TABLE 9. PROTECTED APPLICATIONS OF CASEIN 46 TABLE 10. TECHNICAL APPLICATIONS OF CASEINS AND CASEINATES MARKET AND VOLUME 47 TABLE 11. MAIN APPLICATIONS OF CASEINS AND CASEINATES IN THE FOOD INDUSTRY 2013 - MARKET SIZ 50 TABLE 12. CASEIN HEALTH APPLICATIONS 57 TABLE 13. The world Casein & Caseinates Market volume and value, 2013 58 TABLE 14. CASEINS AVERAGE PRICES BY COUNTRIES 1997-2014 59 TABLE 15. WORLD CASEIN/CASEINATE PRODUCTION /UNIT: 1,000 TONS/ 2005-2014 60 TABLE 16. EXPORT OF CASEIN/CASEINATE 2010-2014 61 TABLE 17. IMPORT OF CASEIN/CASEINATES 2010-2014 61 TABLE 18. US IMPORTS OF CASEINS AND CASEINATES FROM WORLD 2007-2014 IN VALUE 64 TABLE 19. US IMPORT OF CASEIN IN VOLUME (TONS) BY COUNTRY 2010-2014 64 TABLE 20: US IMPORT OF CASEINATE IN VOLUME (TONS) BY COUNTRY 2010-2014 65 TABLE 21. US EXPORT OF CASEIN IN VOLUME 2010-2014 66 TABLE 22. US EXPORT OF CASEIN IN VALUE 2010-2014 66 TABLE 23. US EXPORT OF CASEINATES IN VOLUME 2010-2014 67 TABLE 24. US EXPORT OF CASEINATES IN VALUE 2010-2014 67

TABLE 25. US EXPORTS OF CASEIN GLUES IN VOLUME AND VALUE 2010-2014 68 TABLE 26: US IMPORTS OF CASEIN GLUES IN VOLUME AND VALUE 2010-2014 68 TABLE 27. US IMPORTS OF CASEIN IN VOLUME FROM NEW ZEALAND- 2008-2014 68 TABLE 28. US IMPORTS OF CASEIN IN VALUE FROM NEW ZEALAND- 2008-2014 68 TABLE 29. PRICES OF RENNET AND ACID CASEIN IN THE USA 2005-2013 71 TABLE 30: CANADA - IMPORTS OF CASEIN AND CASEINATE BY CATEGORY IN VOLUME AND VALUE, 2006-2012 TABLE 31: Prices of rennet and acid casein in the USA 2005-2013 74 TABLE 32: Canada - Imports of Casein and Caseinate by category in volume and value, 2007-2011 74 TABLE 33. Canada - Imports & Exports of Casein in Volume Tons 2010-2014 74 TABLE 34. Canada - Imports of Caseinates Volume Tons 2010-2014 76 TABLE 35. Mexico: Imports of Caseinates in 2010-2014 (tons and 000 USD) 76 TABLE 36. Imports of Casein 2010-2014 (tons and USD) 77 TABLE 37. Brazil: Imports of Casein in 2010-2014 (tons and 000 USD) 77 TABLE 38. Brazil: Imports of Caseinates in 2010-2014 (tons and 000 USD) 77 TABLE 39. Chile: Imports of Casein in 2007-2012 (tons and 000 USD) 77 TABLE 40. Chile: Imports of Caseinates in 2010-2014 (tons and 000 USD) 78 TABLE 41. Argentina: Imports/Exports of Casein in 2007-2012 (tons and 000 USD) 78 TABLE 42. Argentina: Imports/Exports of Caseinates in 2009-2013 (tons and 000 USD) 79 TABLE 43. Imports of Casein 2009-2013 by region (in Volume and Value) 79 TABLE 44. Imports/Exports of Caseinates in 2006 by region (in Volume and Value) 79 TABLE 45. Major producers 79 TABLE 46. European Prices 2014 80 TABLE 47. European casein prices 2006/13 80 TABLE 48.. European casein prices 2006/13 80 TABLE 49. European Union: dairy sector 2009-2014 80 TABLE 50. European Union: Production of Casein/ Caseinates (in Volume) -2010-2014 81 TABLE 51. European Union: Subsidies skim milk for the production of Casein & Caseinates ( / 100 kg) 81

TABLE 52. EU BALANCE Sheet for Casein 82 TABLE 53. EU production of casein/ caseinates & Share of Ireland in 1999-2013 (tonnes) 82 TABLE 54. Comparison of Casein/ Caseinates Production figures (2010-2014) 83 TABLE 55. EU export of casein/ caseinates 2010-2014 by country of destination ( tons) 83 TABLE 56.. EU Import of casein/ caseinates 2007-2012 by country of origin 2010-2014 84 TABLE 57. France: Production of Casein/ Caseinates 2006-2014 (In Volume tonnes) 84 TABLE 58.. France: Exports of Casein/ Caseinates (Tons) 2010-2014 84 TABLE 59. France: Imports of Casein/ Caseinates 2010-2014 (In tons) 85 TABLE 60:. Germany: Production of Casein/ Caseinates (in Volume) 2001-2014 85 TABLE 61. Germany: Prices of Edible Casein /kg 1997-2013 85 TABLE 62. Germany - Exports of Casein and Caseinates by country 2011-2014 86 TABLE 63: Germany: Imports of Casein/ Caseinates 2010-2014 86 TABLE 64: Poland: Production of Casein/ Caseinates (in Volume) 87 TABLE 65. Poland: Exports of Casein/ Caseinates 2007-2012 88 TABLE 66. Poland: Imports of Casein/ Caseinates 2010-2014 88 TABLE 67 Netherlands - Exports of Casein and Caseinates by country 2010-2014 89 TABLE 68: Netherlands - Imports of Casein and Caseinates by country 2010-2014 89 TABLE 69: Ireland: Exports of Casein/ Caseinates 2010-2014 90 TABLE 70. Ireland Imports of Casein and Caseinates by country 2010-2014 92 TABLE 71. Denmark - Exports of Casein and Caseinates by country 2010-2014 92 TABLE 72: Denmark Imports of Casein and Caseinates by country 2010-2014 92 TABLE 73. Exports of Casein 2010-2014 93 TABLE 74: : Russia: Imports of Casein by country 2010-2014 93 TABLE 75. Ukraine: Production of Casein/ Caseinates (in Volume) 2010-2014 94 TABLE 76. Belarus: Exports of Casein/ Caseinates 2010-2014 94 TABLE 77. Australia: Production of Casein/ Caseinates (tons) 2010-2014 94 TABLE 78: Australia: Exports and Imports of Casein/ Caseinates (tons) 2010-2014 94 TABLE 79. New Zealand: Production of Casein/ Caseinates (in Volume) 1998-2013 95 TABLE 80: GERMANY - IMPORTS OF CASEIN AND CASEINATES BY COUNTRY 2007-2012 95 TABLE 81. New Zealand: Exports of Casein/Caseinate in Volume 2008-2013 96 TABLE 82. New Zealand Exports of Casein by country 2010-2014 96 TABLE 83: New Zealand Exports of Caseinates 2010-2014 96 TABLE 84. Casein Supplier and Trader in Japan 96 TABLE 85: Japan - Imports of Casein by country in volume (tons) 2010-2014 96 TABLE 86. : Japan Imports of Casein by country in value (1,000 USD) 2010-2014 97

LISTE OF FIGURES FIGURE 1. THREE DIMENSIONAL STRUCTURE OF BOVINE CASEINS 15 FIGURE 2. CASEINS ELECTROPHORESIS 15 FIGURE 3. STRUCTURE OF CASEIN MICELLE (MODEL OF MORR). 16 FIGURE 4. PREPARATION OF MILK FRACTIONS 17 FIGURE 5. CASEIN NUTRACEUTICAL PROPERTIES 26 FIGURE 6. MILK PROTEIN PRODUCTION 34 FIGURE 7: COMPARISON OF WORLD S POPULATION AND MILK PRODUCTION IN THE DIFFERENT GEOGRAPHICAL ZONES FIGURE 8: FUNCTIONAL FOOD AND BEVERAGE INTRODUCTION WORLDWIDE 2005-2009 51 FIGURE 9: EXPORTS FOR SELECTED COUNTRIES 2010/2011 62 FIGURE 10: COMPARISON BETWEEN CASEIN AND CASEINATE TRADE AND PRICES 2007-2012 63 FIGURE 12. DISTRIBUTION OF THE AMERICAN IMPORTS OF CASEINS IN 2012 65 FIGURE 13. DISTRIBUTION OF THE AMERICAN IMPORTS OF CASEINATES IN 2012 66 FIGURE 14. DISTRIBUTION OF THE AMERICAN EXPORTS OF CASEINS IN 2012 67 FIGURE 15. US NON-FAT DRY MILK PRICES COMPARED WITH CASEIN PRICES, 2005-2013 69 FIGURE 16. US- MONTHLY RENNET CASEIN PRICES ($/LB) 2010-2013 70 FIGURE 17:. US- MONTHLY ACID CASEIN PRICES ($/LB) 2010-2013 70 FIGURE 18: CANADA IMPORTS OF DAIRY PRODUCTS IN VALUE (%) 2010 72 FIGURE 19: CANADA IMPORTS OF CASEIN PRODUCTS BY VALUE AND ORIGIN 2010 73 FIGURE 20: CANADA TRADE PARTNERS FOR CASEIN PRODUCTS 2010 73 FIGURE 22. IMPORT OF DAIRY PRODUCTS: 2008 75 FIGURE 23. AUSTRALIAN CASEIN PRODUCTION AND EXPORTS 107 FIGURE 24: 2010/11 CASEIN EXPORTS FROM NEW ZEALAND BY COUNTRY AND MONTH 108 FIGURE 25: NEW ZEALAND EXPORTS OF CASEIN BY COUNTRY OF DESTINATION IN METRIC TONS 2010 109 FIGURE 26. ASIAN CASEIN IMPORTS (VOLUME) FROM THE EU 2007-2011 111 FIGURE 27. MAIN TRADES OF CASEINS AND CASEINATES IN THE WORLD, EXCLUDING INTERNAL EU EXCHANGES ('000 TONS) IN 2012 FIGURE 28. MAIN TRADES OF CASEINS AND CASEINATES WITHIN THE EU ('000 TONS) IN 2012 131

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