EAACI GUIDELINES ON ALLERGEN IMMUNOTHERAPY
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1 4 EAACI GUIDELINES ON ALLERGEN IMMUNOTHERAPY ALLERGIC RHINOCONJUNCTIVITIS Supplementary materials *Graham Roberts 1,2,3, *Oliver Pfaar 4,5, Cezmi A Akdis 6, Ignacio J Ansotegui 7, Stephen R Durham 8, Roy Gerth van Wijk 9, Susanne Halken 10, Désirée Larenas-Linnemann 11, Ruby Pawankar 12, Constantinos Pitsios 13, Aziz Sheikh 14, Margitta Worm 15, Stefania Arasi 16, Moises A Calderon 8, Cemal Cingi 17, Sangeeta Dhami 18, Jean-Luc Fauquert 19, Eckard Hamelmann 20, Peter Hellings 21, Lars Jacobsen 22, Edward Knol 23, Sandra Y Lin 24, Paraskevi Maggina 25, Ralph Mösges 26, Janneke NG Oude Elberink 27, Giovanni B Pajno 28, Elide A Pastorello 29, Martin Penagos 8, Giuseppina Rotiroti 30, Carsten B Schmidt-Weber 31, Frans Timmermans 32, Olympia Tsilochristou 33, Eva-Maria Varga 34, Jamie Wilkinson 35, Andrew Williams 36, Luo Zhang 37, Ioana Agache 38, Elizabeth Angier 39, Montserrat Fernandez-Rivas 40, Marek Jutel 41,42, Susanne Lau 43, Ronald van Ree 44, Dermot Ryan 45, Gunter J Sturm 46,47, Antonella Muraro 48
2 AFFILIATIONS 1 The David Hide Asthma and Allergy Research Centre, St Mary s Hospital, Newport, Isle of Wight, 2 NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, 3 Clinical and Experimental Sciences and Human Development in Health Academic Units, Faculty of Medicine, University of Southampton, Southampton, 4 Department of Otorhinolaryngology, Head and Neck Surgery, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, 5 Center for Rhinology and Allergology, Wiesbaden, 6 Swiss Institute of Allergy and Asthma Research (SIAF), University Zurich, Davos Switzerland. Christine Kühne Center for Allergy Research and Education, Davos, Switzerand 7 Department of Allergy and, Hospital Quironsalud Bizkaia, Erandio - Bilbao, Spain 8 Allergy and Clinical, National Heart and Lung Institute, Imperial College London, 9 Section of Allergology, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, 10 Hans Christian Andersen Children s Hospital, Odense University Hospital, Odense, Denmark 11 Center of Excellence in Asthma and Allergy, Hospital Médica Sur, Mexico City, Mexico 12 Dept. of Pediatrics, Nippon Medical School, Tokyo, Japan 13 Medical School, University of Cyprus, Nicosia, Cyprus 14 Asthma Centre for Applied Research, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, 15 Department of Dermatology and Allergy, Charité Campus Mitte, Universitätsmedizin Berlin, Berlin, 16 Department of Pediatrics, Allergy Unit, University of Messina, Messina, Italy; Molecular Allergology and Immunomodulation- Department of Pediatric Pneumology and, Charite Medical University, Berlin, 17 Medical Faculty, Dept of Otorhinolaryngology, Eskisehir Osmangazi University, Eskisehir, Turkey 18 Evidence Based Health care Ltd, Edinburgh, 19 CHU Clermont-Ferrand University Hospital (CHU Estaing), Unité d allergologie de l enfant, Clermont-Ferrand, France 20 Children s Hospital Bel, EvKB, University Bielefeld, 21 Dept of Otorhinolaryngology, Univ. Hospitals Leuven, Belgium and Dept of Otorhinolaryngology, Academic Medical Center Amsterdam, Amsterdam, The 22 Allergy Learning and Consulting, Copenhagen, Denmark 23 Depts. and Dermatology/Allergology, University Medical Center Utrecht, Utrecht, The 24 Johns Hopkins Dept of Otolaryngology-Head & Neck Surgery, Baltimore, USA 25 Allergy & Clinical Unit, 2nd dpt of Pediatrics, NKUA Ans University, Ans, Greece 26 Clinical Research International Ltd., Hamburg, 27 University Medical Center of Groningen, University of Groningen, Groningen, The 28 Department of Pediatrics, Allergy Unit, University of Messina, Messina, Italy 29 University of Milano, Department of Allergy and, Asst Grande Ospedale Metropolitano Niguarda, Milano, Italy 30 Department of Allergy and Medical Rhinology, The Royal National Throat Nose and Ear Hospital, University College Hospital, London, 31 Center of Allergy and Environment (ZAUM) & Institute of Allergy Research, Helmholtz Center Munich, Munich, 32 European Anaphylaxis Taskforce - Nederlands Anafylaxis Netwerk, Dordrecht, The 33 Division of Asthma, Allergy and Lung Biology, Department of Paediatric Allergy, Children s Allergy Service, King s College London & Guy s and St. Thomas National Health Service Foundation Trust, London, 34 Dept. of Paediatric and Adolescent Medicine, Respiratory and Allergic Disease Division, Medical University of Graz, Graz, Austria 35 Pharmaceutical Group of European Union, Brussels, Belgium 36 Allergy Department Guys & St Thomas NHS Foundation Trust, London, 37 Department of Otolarlyngology Head & Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China 38 Transylvania University Brasov, Faculty of Medicine, Department of Allergy and Clinical, Brasov, Romania 39 Department of Clinical and Allergy, Norrn General Hospital, Herries Road, Sheffield, 40 Allergy Department, Hospital Clinico San Carlos, IdISSC, Madrid, Spain 41 ALL-MED Medical Research Institute, Wroclaw, Poland 42 Wroclaw Medical University, Wroclaw, Poland 43 Department of Pediatric Pneumology and, Charité Universitätsmedizin, Berlin, 44 Departments of Experimental and of Otorhinolaryngology, Academic Medical Center, University of Amsterdam, Amsterdam, The 45 Usher Institute of Population Health Sciences and Informatics, University of Edinburgh Medical School, Edinburgh, 46 Department of Dermatology and Venerology, Medical University of Graz, Graz, Austria 47 Outpatient Allergy Clinic Reumannplaz, Vienna, Austria 48 Department of Women and Child Health, Referral Centre for Food Allergy Diagnosis and Treatment Veneto Region, University of Padua, Padua, Italy *Denotes equal contribution
3 EAACI Guideline: AIT for Rhinoconjunctivitis Table S1 Details of authors Name Discipline, expertise Institution Graham Roberts Oliver Pfaar Cezmi A. Akdis Ignacio J. Ansetegui Stephen Durham Roy Gerth van Wijk Susanne Halken Désirée Larenas- Linnemann Ruby Pawankar Constantinos Pitsios Aziz Sheikh Margitta Worm Professor of Paediatric Allergy and Respiratory Medicine Associate Professor of Otorhinolaryngology, Otorhinolaryngologist, Professor of Medicine & Clinical and Experimental MD, PhD. President Elect of World Allergy Organization (WAO). Head of Department of Allergy & Professor of Allergy Professor of Allergology The David Hide Asthma and Allergy Research Centre, St Mary s Hospital; NIHR Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust; Faculty of Medicine, University of Southampton Department of Otorhinolaryngology, Head and Neck Surgery, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University; Center for Rhinology and Allergology Swiss Institute of Allergy and Asthma Research, University Zurich Department of Allergy &, Hospital Quironsalud Bizkaia National Heart and Lung Institute, Imperial College Section of Allergology, Department of Internal Medicine, Erasmus Medical Center Professor, Consultant Hans Christian Andersen Children s Hospital, Odense University Hospital in Paediatrics and Paediatric Allergology and Pediatrician, National Hospital Médica Sur Center of Excellence in Asthma and Allergy, Investigator grade II, Head Allergy Clinic and Allergy Consultant at Hospital Médica Sur. Professor of Paediatric Allergy Teaching Faculty Member; Physiology, Allergology, Professor of Primary Care Research & Development and Consultant Paediatric Professor of dermatology Department of Pediatrics, Nippon Medical School, Tokyo, Japan Medical School, University of Cyprus Asthma Centre for Applied Research, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh Medical School Dpt of Dermatology and Allergy, Charite-Universitätsmedizin Geographical location Newport Isle of Wight, Southampton, Mannheim, Wiesbaden, Davos, Switzerland Bilbao, Spain London, Rotterdam, Odense, Denmark Mexico City, Mexico Tokyo, Japan Nicosia, Cyprus Edinburgh, Berlin, Description of role in guideline Conceived paper, drafted sections, edited sections into initial draft document, critically Conceived paper, drafted sections, edited sections into initial draft document, critically Drafted section, critically reviewed and edited Methodolgical support throughout guideline production process, contributed to writing guideline and providing critical comments on various drafts of Guideline Supplementary materials EAACI E-21
4 EAACI Guideline: AIT for Rhinoconjunctivitis Table S1 Continued Name Discipline, expertise Institution Stefania Arasi Moisés A. Calderon Cemal Cingi Sangeeta Dhami Jean L. Fauquert Eckard Hamelmann Peter Hellings Lars Jacobsen Edward F. Knol Sandra Y Lin Paraskevi Maggina Ralph Mösges Hanneke Oude Elberink Giovanni B. Pajno Elide Pastorello Martin Penagos Giuseppina Rotiroti Carsten Schmidt- Weber Pediatrician, pediatric allergologist, metodologist, MD, PhD Professor of Internal Medicine and Clinical Allergy ENT GP, Director of Evidence Based Health Care Ltd Ophthmologist Department of Pediatrics, Allergy Unit, University of Messina, Italy and Department of Pediatric Pneumology and, Charité Universitätsmedizin Berlin Allergy and Clinical, National Heart and Lung Institute, Imperial College London Department of ENT, Eskisehir Osmangazi University Medical Faculty Evidence-Based Health Care Ltd CHU Clermont-Ferrand University Hospital (CHU Estaing), Unité d allergologie de l enfant, INSERM Children s Center Bel, EvKB, Bielefeld, and Allergy Center Buhr-University Laboratory of Experimental, University Hospitals Geographical location Messina, Italy; Berlin, London, Eskisehir, Turkey Edinburgh, Clermont- Ferrand, France Bochum, Leuven, Belgium Professor of paediatric allergy Professor of Otorhinolaryngology Immunologist ALC, Allergy Learning and Consulting Copenhagen, Denmark Associate Professor Department of and Department Utrecht, and Dermatology/Allergology of Dermatology & Allergology, University Medical Center Professor of Otorhinolaryngology Professor of Pediatrics; Consultant of Pediatric Allergology Johns Hopkins Dept of Otolaryngology-Head & Neck Surgery Allergy and Clinical Unit, 2nd Department of Pediatrics, University of Ans, P&A Kiriakou Children s Hospital Institute of Medical Statistics, Informatics and Epidemiology, Medical Faculty, University at Cologne Department of Allergology and Internal Medicine, University of Groningen, University Medical Hospital Groningen, Groningen, The ; Groningen Research Center for Asthma and COPD (GRIAC) Department of Pediatrics, Allergy Unit, University of Messina Baltimore, USA Ans, Greece Cologne, Groningen, Messina, Italy University of Milano Milano, Italy Section of Allergy and Clinical, London, National Heart and Lung Institute, Imperial College London, Royal Brompton Hospital The Royal National Throat, Nose and Ear London, Hospital, University College London Immunologist Zentrum Allergie & Umwelt (ZAUM), Technische Universität und Helmholtz Zentrum München München, Description of role in guideline Methodological support, revising and editing of Methodological support, revising and editing of E-22 EAACI Supplementary materials
5 EAACI Guideline: AIT for Rhinoconjunctivitis Table S1 Continued Name Discipline, expertise Institution Frans Timmermans Olympia Tsilochristou Eva-Maria Varga Jamie Wilkinson Andrew Williams Luo Zhang Ioana Agache Elizabeth Angier Montserrat Fernandez- Rivas Marek Jutel Susanne Lau Ronald van Ree Dermot Ryan Gunter Sturm Antonella Muraro Health, Safety, Environment and Quality Consultant and acting as Secretary General of NAN/EAT Nederlands Anafylaxis Netwerk European Anaphylaxis Taskforce Department of Paediatric Allergy, Division of Asthma, Allergy and Lung Biology, King s College London, Guy s and St Thomas Hospital NHS Foundation Trust Associate Professor of Department of Pediatric and Adolescent Paediatrics; Consultant Medicine, Respiratory and Allergic Disease Paediatric Pulmonologist and Division, Medical University of Graz Pharmacist Pharmaceutical Group of European Union Allergy nurse Guy s and St Thomas NHS Foundation Trust Professor of Otorhinolaryngology Beijing Institute of Otolarygology Associate Professor Allergy and Clinical General Practitioner with an Interest in Allergy Transylvania University Brasov, Faculty of Medicine, Department of Allergy and Clinical Department of Clinical and Allergy, Norrn General Hospital MD, PhD,, Head Allergy Department, Hospital Clinico San Allergy Department Carlos, IdISSC Hospital Clinico San Carlos, Associate Professor Medicine Universidad Complutense de Madrid prof. dr hab. Wroclaw Medical University, Wroclaw, Poland; ALL-MED Medical Research Institute Professor of Pediatrics. Department of Pediatric Pneumology and Section Head for Pediatric, Charité Universitätsmedizin Pneumology and Allergy. Professor of Molecuar and Translational Allergology Retired GP. Clinical Research Fellow Associate Profesor of Dermatology and Venerology Head Departments of Experimental and of Otorhinolaryngology, Academic Medical Center, University of Amsterdam Usher Institute of Population Health Sciences and Informatics, University of Edinburgh Medical School Department of Dermatology and Venerology, Medical University of Graz; Outpatient Allergy Clinic Reumannplatz Professor of Pediatric Department of Mor and Child Health, Allergy_Head of The Referral Centre for Food Allergy Food Allergy Referral Diagnosis and Treatment Veneto Region, Centre Department of University of Padua Women and Child Health All authors fulfilled authorship criteria. Geographical location Dordrecht, London, Graz, Austria Brussels, Belgium London, Beijing, China Brasov, Romania Sheffield, Madrid, Spain Wroclaw, Poland Berlin, Amsterdam, Edinburgh, Vienna, Austria Padua, Italy Description of role in guideline Chair of Guidelines project; involved in planning of guideline document; critically reviewed draft guideline. Member of Rhinoconjunctivitis AIT TF Supplementary materials EAACI E-23
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