Pro ceed ings of the 22 nd Meet ing. WORKING GROUP on PROLAMIN ANAL Y SIS and TOX IC ITY. Edited by Mar tin Stern Uni ver sity of Tübingen

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1 Pro ceed ings of the 22 nd Meet ing WORKING GROUP on PROLAMIN ANAL Y SIS and TOX IC ITY Edited by Mar tin Stern Uni ver sity of Tübingen Verlag Wissenschaftliche Scripten 2008

2 Impressum Pro ceed ings of the 22 nd Meet ing WORK ING GROUP on PROLAMIN ANAL Y SIS and TOX IC ITY Sep tem ber, 2007 Dublin, Ireland Wichtiger Hinweis: Das Werk, einschließlich aller seiner Teile, ist urheberrechtlich geschützt. Jede Verwertung außerhalb der engen Grenzen des Urheberrechtgesetzes ist ohne Zu stim mung des Ver la ges un zu läs sig und straf bar. Das gilt ins be son de re für Ver viel fäl ti gun gen, Über set zun gen, Mi kro ver fil mun gen und die Ein spei che rung und Ver ar bei tung in elek tro ni schen Sys te men. Scientific Organisation Prof. Dr. Mar tin Stern Universitätsklinik für Kinder- und Jugendmedizin Hoppe-Seyler-Straße 1, TÜBINGEN, GER MANY Phone ; Tele fax mar tin.stern@med.uni-tuebingen.de Host Conleth Feighery, MD Professor of Immunology University of Dublin, Department of Immunology St. James's Hospital and Trinity College Dublin James's Street DUBLIN 8, IRELAND Phone /2541 (direct line) Phone /2928; Telefax con.feighery@tcd.ie Cover picture Thomas Mothes 2008 Verlag Wissenschaftliche Scripten ISBN:

3 Table of contents 7 Ta ble of con tents In tro duc tion... 3 Ex ec u tive Sum mary... 5 List of Participants Pro gram I. An a lyt i cal re search re ports R. van Eckert, J. Bond, P. Raw son, C. L. Klein, M. Stern, T. W. Jor dan Reaction of selected antibodies with gliadin from Eu ro pean wheat J. R. Mujico, M. C. Mena, M. Lombardía, A. Hernando, H. Wieser, E. Méndez On the way to re li able quan ti fi ca tion of bar ley hordeins us ing the R5 ELISA tech nique V. Doña, M. Urrutia, M. Bayardo, F. Goldbaum, F. G. Chirdo De vel op ment of a quan ti ta tive immunoassay for glu ten-free food anal y sis based on a new an ti gen-bind ing strat egy I. Malmheden Yman, B. Kruse Glu ten in oat and nat u rally glu ten-free prod ucts; gliadin in beer, soy sauces and glu cose syr ups D. Gabrovská, J. Rysová, I. Paulícková, J. Prokeš, J. Škach Glu ten-free beer: a new chance for coeliacs? F. W. Janssen, F. van Klinken, U. Immer, C. Gößwein Safety of Asian soy sauces in a glu ten-free diet... 55

4 8 Table of contents U. Immer, C. Gößwein, S. Haas-Lauterbach RIDASCREEN Gliadin competitive - New as say for mat for the R5 an ti body L. Dekking, Y. Kooy-Winkelaar, M. Salden, R. Verheijen, N. Sajic, J.-W. Drijfhout, F. Koning Gluten-Tec a novel glu ten de tec tion kit II. Clin i cal re search re ports S. Castellaneta, F. Aniballi, E. Fabiani, L. Saturni, E. Lionetti, R. Francavilla, S. Kulpuru, A. Fassano, C. Catassi In fant nu tri tion and de vel op ment of coeliac dis ease in ge net i cally at-risk ba bies: a di etary in ter ven tion study at wean ing K. Kaukinen, M. Mäki Self-de tec tion of coeliac dis ease through a transglutaminase-based an ti body: from lab o ra tory to onsite test ing C. Prause, M. Ritter, W. Schlumberger, C. Probst, C. Dähnrich, R. Lieske, H. Uhlig, T. Richter, M. Stern, M. Laass, A. C. Hauer, K.-P. Zimmer, T. Mothes The new gen er a tion of gliadin an ti bod ies for di ag no sis of coeliac dis ease V. F. Zevallos, P. J. Ciclitira, T. Suligoj, L. I. Herencia, H. J. Ellis In vi tro safety as sess ment of quinoa (Chenopodium quinoa Willd.) in coeliac dis ease C. O'Brien, C. Feighery A novel com pu ta tional ap proach for screen ing prolamin se quences for immunogenic re gions in coeliac dis ease C. Mitea, L. Dekking, R. Havenaar, L. Edens, F. Koning Coeliac disease: enzymatic gluten degradation as a therapeutic option

5 Table of contents 9 III. Im mu nol ogy of coeliac dis ease and Co dex stan dard for glu ten-free foods B. Meresse, G. Malamut, N. Cerf-Bensussan The in ter play be tween adap tive and in nate im mu nity in coeliac dis ease: the role of IL K. Sjölin The saga of the glu ten-free stan dard H. Deutsch Com ment to the Draft Re vised Stan dard for Glu ten-free Foods at Step 6 - ALINORM 07/30/26, Appendix IV ALINORM 08/31/26, Ap pen dix III Draft re vised co dex stan dard for foods for spe cial di etary use for per sons in tol er ant to glu ten IV. Per spec tives and ac tion plan M. Stern Perspectives and action plan In memoriam Pro fes sor Enrique Méndez