Evolva. World Congress on Industrial Biotechnology, Montreal Stephan Herrera VP, Strategy & Public Affairs

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1 Evolva World Congress on Industrial Biotechnology, Montreal 2015 Stephan Herrera VP, Strategy & Public Affairs

2 Disclaimer The shares of Evolva Holding ( Evolva ) are traded on the SIX Swiss Stock Exchange (ticker: EVE ). This presentation may contain specific forward-looking statements, relating to Evolva's future business, development and economic performance. e.g., statements including terms like "believe", "assume", "expect" or similar expressions. Such forward-looking statements are subject to known and unknown risks, uncertainties and other factors which may result in a substantial divergence between the actual results, financial situation, development or performance of Evolva and those explicitly or implicitly presumed in these statements. Against the background of these uncertainties readers should not rely on forward-looking statements. Evolva assumes no responsibility to update forward-looking statements or to adapt them to future events or developments. Evolva Proprietary Material Slide 2

3 Evolva Snapshot Snapshot: Developing/producing functional, sustainable, and cost-effective ingredients for health, wellness, and nutrition Based in Basel, Switzerland with operations in Denmark, the UK, India and the US ~150 employees Listed on the Swiss Stock Exchange (EVE.SW) Technology platform: Biosynthesis and fermentation Evolva Proprietary Material Slide 3

4 Hundreds Of Ingredients Have Supply Chain Issues Resveratrol Skin Aging Citrus Stevia Adiposity Mogroside Nootkatone Frankincense Huperzine Blueberry Ginger Azulene Rowan Caffeine Jasmonates Saffron UV blockers Androgens Cloves Raspberry Ergot Ginseng Heparin Mint Cocoa Gibberellins Opiates Abscisic A. Humulene Betanin Insct Phmns Taxol Propolis Agarwood Indigo Sandalwood Carmine Breast Milk Vanillin Unavailable Evolva Proprietary Material Slide 4

5 But If You Move Their Genes Into Yeast. Resveratrol Stevia Nootkatone Yeast Evolva Proprietary Material Slide 5

6 . You Can Make Them All By Brewing Resveratrol Skin Aging Citrus Stevia Adiposity Mogroside Nootkatone Frankincense Huperzine Blueberry Ginger Azulene Rowan Caffeine Jasmonates Saffron UV blockers Androgens Cloves Raspberry Ergot Ginseng Heparin Mint Cocoa Gibberellins Opiates Abscisic A. Humulene Betanin Specialist Brewing for the 21 st Century Insct Phmns Taxol indicative examples only Propolis Agarwood Indigo Sandalwood Carmine Breast Milk Vanillin Unavailable Evolva Proprietary Material Slide 6

7 Fermentation Ingredients All Produced From Same Process 21 st Century Brewing Sugar (US or EU grown) Vitamins & Minerals Baker s Yeast Technology Platform Metabolically enhanced Baker s Yeast Purification Product Production currently handled through contractors or partners Will gradually internalise capability as product sales justify Evolva Proprietary Material Slide 7

8 Key Products Launched Vanillin and Resveratrol in 2014 Nootkatone will be launched this year Vanillin 2014 Resveratrol 2014 Nootkatone 2015 Stevia and Saffron in 2016 Stevia 2016 Saffron Evolva Proprietary Material Slide

9 Resveratrol The good stuff in red wine BUT you need 6+ bottles/day to get enough Main source = knotweed roots (from China) Invasive plant pest. Issues on quality, supply, support Evolva s Resveratrol High quality, natural & sustainable Stable supply chain, affordable Resveratrol Supports Healthy Ageing Protects Against Oxidative Stress Reduces Vascular Inflammation Main source of mortality and morbidity in diabetes Mimics Caloric Restriction 15-70% gain in life span in animals Over time move into diabetic nutrition, pet health etc. Evolva Proprietary Material Slide 9

10 Vanillin >98% of world s vanillin comes from synthetic chemistry Vanillin & Vanilla Essence World Consumption (Tonnes) Cannot supply world demand by growing vanilla orchids 1500 Evolva s vanillin Good taste and aroma Natural (under EU and US law) and sustainable Affordable Simple, stable supply chain Petrochemicals Chemically Treated Lignin Ferulic Acid & Eugenol Vanilla Orchid (Bean) * Market data collated from various sources Evolva Proprietary Material Slide 10

11 Nootkatone The characteristic aroma of grapefruits A GRAS food ingredient But only % of grapefruit oil Initial use in flavors and fragrance But also kills & deters many nuisance insects Ticks, mosquitoes, bed bugs etc. Efficacious but non toxic Skin creams, sprays, supermarket traps etc. US Centers for Disease Control has shown Nootkatone is highly effective against the ticks that transmit Lyme Disease Revenue potential: > USD 100 million p.a. But will have to go through regulatory process for pest control Evolva Proprietary Material Slide 11

12 Stevia Stevia is a natural, zero-calorie sweetener A mixture of sweet molecules, some bitter tasting But, you need to compromise taste, calories, or both Best tasting molecules occur at low concentrations in plant & expensive to use in large volume products Evolva can make the best tasting molecules by brewing 1 tonne of dried plant gives 1kg of Reb D And make them available in large scale at an affordable price Evolva Proprietary Material Slide 12

13 Saffron World s most expensive spice c. $1,500/kilo Use limited by cost - 250,000 flowers to make 1 kilo Use limited by supply chain - 95% of production in Iran Affordable product with dependable supply will allow Greater traditional use Use of saffron in consumer brands (like vanillin used now) Dairy Meats Snacks Soaps Textiles Evolva Proprietary Material Slide 13

14 Mind The Gap: Key Learnings & Horizon Media & social media NGOs Partnering on all fronts Policymakers & their advisors UN CBD & Nagoya Transparency Sustainability Evolva Proprietary Material Slide 14

15 Thank You ww With Apologies & Credit to HSBC & JWT Evolva Proprietary Material Slide 15