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1 Supplementary material Nutrients Coffee and Tea Consumption and the Contribution of Their Added Ingredients to Total Energy and Nutrient Intakes in 10 European Countries: Nineteen Nineties Benchmark Data. Edwige Landais 1, Aurélie Moskal 2, Amy Mullee 2,3 Geneviève Nicolas 2, Marc Gunter 2, Inge Huybrechts 2, Kim Overvad 4, Nina Roswall 5, Aurélie Affret 6, Guy Fagherazzi 6, Yahya Mahamat- Saleh 6, Verena Katzke 7, Tilman Kühn 7, Carlo La Vecchia 8,9, Antonia Trichopoulou 8, Elissavet Valanou 8, Calogero Saieva 10, Maria Santucci de Magistris 11, Sabina Sieri 12, Tonje Braaten 13, Guri Skeie 13, Elisabete Weiderpass 14,15,16,17, Eva Ardanaz 18,19, Maria-Dolores Chirlaque 19,20,21, Jose Ramon Garcia 22, Paula Jakszyn 23, Miguel Rodríguez-Barranco 19,24,25, Louise Brunkwall 26, Ena Huseinovic 27, Lena Nilsson 28, Peter Wallström 26, Bas Bueno-de-Mesquita 29,30, Petra H. Peeters 31, Dagfinn Aune 29, Tim Key 32, Marleen Lentjes 33, Elio Riboli 29, Nadia Slimani 2, Heinz Freisling 2 * Contact: Nutrition and Metabolism Section, International Agency for Research on Cancer, Lyon, France; MoskalA@iarc.fr (A.M.); nicolasg@iarc.fr (G.N.); gunterm@iarc.fr (M.G.); huybrechtsi@iarc.fr (I.H.); n.popovic@orange.fr (N.S.); freislingh@iarc.fr (H.F.) 1
2 0% 20% 40% 60% 80% 100% Centres Greece Granada Murcia Navarra San Sebastian Asturias Ragusa Florence Turin Varese Heidelberg Potsdam Bilthoven UK General population UK Health conscious Copenhagen Aarhus Malmo Umea Total Coffee only Tea only Coffee & tea Non-consumers Figure S1. Percentages of consumers and non-consumers of coffee and tea among men the day of the 24-h recall by centre. 2
3 0% 20% 40% 60% 80% 100% Greece Granada Murcia Navarra San Sebastian Asturias Ragusa Naples Florence Turin Varese South coast of France South of France North-East of France North-West of France Heidelberg Potsdam Bilthoven Utrecht UK General population UK Health conscious Copenhagen Aarhus Malmo Umea South & East of Norway North & West of Norway Total Centres Coffee only Tea only Coffee & tea Non-consumers Figure S2. Percentages of consumers and non-consumers of coffee and tea among women the day of the 24-h recall by centre. 3
4 0% 20% 40% 60% 80% 100% Centres Greece Granada Murcia Navarra San Sebastian Asturias Ragusa Florence Turin Varese Heidelberg Potsdam Bilthoven UK General population UK Health conscious Copenhagen Aarhus Malmo Umea Total Coffee with caffeine Decaffeinated coffee Figure S3. Percentage of consumers of coffee with caffeine and decaffeinated coffee among men who consumed coffee the day of the 24-h recall by centre. 4
5 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Centres Greece Granada Murcia Navarra San Sebastian Asturias Ragusa Naples Florence Turin Varese South coast of France South of France North-East of France North-West of France Heidelberg Potsdam Bilthoven Utrecht UK General population UK Health conscious Copenhagen Aarhus Malmo Umea South & East of Norway North & West of Norway Total Coffee with caffeine Decaffeinated coffee Figure S4. Percentage of consumers of coffee with caffeine and decaffeinated coffee among women who consumed coffee the day of the 24-h recall by centre. 5
6 Table S1. Mean daily intake of coffee and tea (g/day) by type and country in the EPIC calibration study population based on 24-HDR among men and women Coffee & Tea* Coffee Tea* Herbal tea Chicory & substitutes Country Sex n fully adjusted mean 1 SEM 2 fully adjusted mean 1 SEM 2 fully adjusted mean 1 SEM 2 fully adjusted mean 1 SEM 2 fully adjusted mean 1 SEM 2 Italy Male Spain Male United Kingdom Male The Netherlands Male Greece Male Germany Male Sweden Male Denmark Male France Female Italy Female Spain Female United Kingdom Female The Netherlands Female Greece Female Germany Female Sweden Female Denmark Female Norway Female * Either green or black tea, herbal tea excluded. 1 Adjusted for age, total energy intake, weight, height and weighted by season and day of recall. 2 SEM standard error of the mean. 6
7 Table S2. Fully adjusted mean 1 daily intake of coffee and tea (g/day) by smoking status and sex in the EPIC calibration study population based on 24-HDR across EPIC centres ordered from South to North Men Women Country & Centre Never Former Current p- Never Former Current p- n All n All smoker smoker smoker trend smoker smoker smoker trend Greece (13.7) (24.2) (21.6) (23.0) (12.8) (14.5) (48.5) (29.0) Spain Granada (32.0) (54.0) (48.8) (63.7) (25.8) (27.7) (112.9) (81.5) Murcia (30.1) (54.0) (54.5) (46.4) (25.7) (29.0) (93.9) (63.7) Navarra (22.4) (37.0) (50.7) (32.3) (27.0) (31.8) (79.4) (63.6) San Sebastian (21.5) (36.7) (41.1) (32.4) (28.5) (33.2) (74.8) (76.0) Asturias (23.9) (40.0) (40.6) (41.5) (24.8) (28.2) (92.9) (59.0) Italy Ragusa (36.2) (65.2) (51.6) (74.9) (38.1) (57.9) (84.2) (61.4) Naples (22.3) (31.3) (49.1) (39.9) Florence (28.6) (54.1) (40.4) (56.9) (15.9) (22.7) (32.1) (29.8) Turin (18.2) (34.0) (26.7) (34.5) (22.5) (28.5) (47.2) (54.3) Varese (25.9) (42.7) (40.1) (52.5) (15.9) (18.7) (42.1) (39.5) France South Coast (18.3) (20.7) (43.7) (71.3) South (12.2) (14.2) (25.7) (45.5) North East (10.2) (11.7) (22.9) (38.0) North West (18.1) (21.5) (37.7) (63.9) Germany Heidelberg (14.6) (24.9) (21.6) (30.2) (13.7) (18.8) (25.1) (29.7) Potsdam (13.3) (23.4) (19.2) (28.0) (13.7) (17.0) (29.1) (35.8) The Netherlands Bilthoven (15.2) (29.7) (23.2) (24.4) (13.9) (23.1) (23.9) (23.4) Utrecht (10.5) (15.1) (17.5) (23.2) United Kingdom General Population (23.4) (38.0) (34.0) (55.2) (18.7) (23.8) (34.5) (59.1) Health Conscious (44.1) (68.8) (67.4) (99.5) (31.8) (38.9) (55.8) (206.8) Denmark Copenhagen (12.8) (22.9) (20.3) (22.2) (11.6) (16.3) (22.1) (23.5) Aarhus (19.7) (37.6) (31.4) (32.5) (19.7) (28.6) (37.2) (38.3) Sweden Malmö (13.2) (22.3) (19.2) (24.7) (11.0) (15.6) (20.2) (22.0)
8 Umeå (13.0) (17.6) (23.0) (30.6) (11.3) (13.9) (27.2) (26.6) Norway South & East (14.7) (23.5) (24.3) (27.4) North & West (16.4) (27.1) (26.8) (30.1) Adjusted for age, total energy intake, weight, height and weighted by season and day of recall. If a group comprised fewer than 20 persons, mean intake is not presented. 8
9 Table S3. Fully adjusted mean 1 daily intake of coffee and tea (g/day) by physical activity level and sex in the EPIC calibration study population based on 24- HDR across EPIC centres ordered from South to North Men Women Country & Centre Moderately Moderately p- Moderately Moderately p- n All Inactive Active n All Inactive Active Inactive Active trend Inactive Active trend Greece (13.4) (33.4) (21.3) (20.8) (47.6) (12.3) (47.0) (27.3) (15.0) (37.5) Spain Granada (32.2) (70.6) (58.0) (52.3) (91.9) (25.4) (171.0) (91.5) (27.1) (134.6) Murcia (30.3) (58.8) (54.0) (55.3) (81.0) (25.2) (104.1) (63.0) (29.4) (102.7) Navarra (22.5) (51.3) (41.4) (36.5) (56.7) (26.6) (112.4) (76.9) (30.0) (122.2) San Sebastian (21.6) (44.6) (43.7) (34.3) (53.5) (28.0) (101.5) (64.0) (35.3) (83.7) Asturias (24.0) (57.0) (42.0) (42.4) (54.6) (24.3) (106.3) (67.7) (28.2) (83.0) Italy Ragusa (36.4) (67.2) (65.2) (64.2) (118.9) (37.5) (130.0) (86.0) (46.7) (120.8) Naples (21.9) (59.2) (35.1) (33.7) (84.4) Florence (28.5) (54.8) (48.8) (51.3) (95.3) (15.6) (48.6) (31.8) (20.4) (55.6) Turin (18.1) (35.6) (30.8) (32.7) (56.7) (22.1) (64.7) (49.8) (29.2) (62.6) Varese (26.0) (67.0) (42.1) (41.8) (86.3) (15.6) (50.5) (36.2) (19.5) (51.2) France South Coast (17.6) (45.8) (21.9) (40.3) (110.8) South (11.7) (29.5) (14.4) (27.7) (81.4) North East (9.7) (22.8) (12.1) (23.6) (79.4) North West (17.5) (45.7) (21.1) (42.8) (137.9) Germany Heidelberg (14.7) (32.8) (26.3) (23.2) (45.7) (13.5) (34.1) (23.4) (20.1) (44.0) Potsdam (13.4) (35.4) (28.1) (18.2) (42.1) (13.5) (29.7) (24.3) (20.0) (65.4) The Netherlands Bilthoven (15.3) (42.7) (31.5) (21.8) (33.7) (13.7) (48.2) (29.6) (17.9) (34.5) Utrecht (10.3) (42.5) (20.8) (14.1) (23.3) United Kingdom General (23.4) (58.9) (43.8) (36.9) (58.3) (18.3) (45.5) (33.3) (27.9) (55.3) Population Health Conscious (44.5) (112.7) (84.0) (67.9) (114.7) (31.2) (64.1) (60.9) (45.8) ) Denmark Copenhagen (12.9) (24.5) (24.5) (23.1) (32.1) (11.4) (21.2) (19.0) (20.9) (44.5) Aarhus (19.8) (39.5) (36.5) (33.8) (54.9) (19.4) (39.5) (31.6) (33.8) (75.6)
10 Sweden Malmö (13.4) (29.0) (19.7) (21.9) (63.4) (10.9) (25.0) (16.9) (17.4) (49.7) Adjusted for age, total energy intake, weight, height and weighted by season and day of recall. If a group comprised fewer than 20 persons, mean intake is not presented. No physical activity level was measured in Norway, and Umeå. 10
11 Table S4. Fully adjusted mean 1 daily intake of coffee and tea (g/day) by BMI groups and sex in the EPIC calibration study population based on 24-HDR across EPIC centres ordered from South to North Men Women Country & Centre BMI < BMI BMI p- BMI BMI BMI p- n All n All 25kg/m kg/m 2 30kg/m 2 trend < 25kg/m kg/m 2 30kg/m 2 trend Greece (12.9) (30.3) (17.3) (24.4) (12.1) (24.8) (19.3) (19.6) Spain Granada (31.8) (121.6) (38.5) (62.4) (25.6) (50.6) (37.3) (48.7) Murcia (29.8) (62.6) (40.0) (62.9) (25.5) (44.9) (40.4) (47.6) Navarra (22.1) (55.0) (28.6) (44.2) (27.0) (44.0) (41.0) (60.9) San Sebastian (21.3) (44.6) (26.9) (51.6) (28.4) (39.9) (47.0) (78.3) Asturias (23.7) (56.2) (30.6) (48.9) (24.7) (42.7) (34.8) (59.9) Italy Ragusa (35.9) (81.1) (45.0) (85.6) (38.0) (52.6) (64.7) (101.3) Naples (22.1) (39.4) (35.0) (41.0) Florence (28.2) (46.5) (39.8) (77.2) (15.9) (22.3) (26.3) (43.2) Turin (17.9) (31.4) (23.9) (50.7) (22.4) (30.8) (39.4) (57.9) Varese (25.7) (41.8) (34.7) (90.9) (15.7) (22.0) (26.7) (41.3) France South coast (17.9) (20.0) (45.2) (75.4) South (11.8) (13.5) (25.7) (61.2) North-East (9.8) (11.7) (20.0) (41.6) North-West (17.7) (20.2) (39.3) (93.0) Germany Heidelberg (14.6) (25.4) (20.5) (34.2) (13.6) (17.7) (25.8) (36.2) Potsdam (13.3) (25.1) (18.2) (29.6) (13.7) (20.2) (23.1) (31.1) The Netherlands Bilthoven (15.1) (25.4) (20.4) (38.4) (13.8) (19.2) (23.1) (35.0) Utrecht (10.4) (15.1) (16.9) (25.3) United Kingdom 11
12 General (23.1) (39.3) (31.5) (65.4) (18.6) (25.9) (31.3) (50.5) population Health conscious (43.7) (49.8) (94.6) (300.5) (31.7) (35.7) (76.9) (148.7) Denmark Copenhagen (12.6) (20.9) (18.1) (32.3) (11.5) (16.1) (19.6) (30.1) Aarhus (19.6) (33.5) (26.8) (52.7) (19.7) (25.5) (36.4) (57.3) Sweden Malmö (13.0) (21.4) (17.4) (33.6) (11.0) (15.7) (17.9) (26.9) Umeå (12.7) (20.9) (17.6) (37.3) (11.2) (16.1) (18.3) (29.7) Norway South & East (14.2) (16.9) (28.6) (59.1) North & West (16.0) (19.9) (29.5) (57.2) Adjusted for age, total energy intake, weight, height and weighted by season and day of recall. If a group comprised fewer than 20 persons, mean intake is not presented. 12
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